| Date | Game | Result | Notes |
| 12/12/1921 | UNC @ Durham YMCA | L 18-41 | |
| 1/12/1922 | UNC vs. South Carolina | W 44-28 | |
| 1/14/1922 | UNC vs. Durham YMCA | L 25-46 | |
| 1/19/1922 | UNC @ Wake Forest | W 32-28 | |
| 1/23/1922 | UNC @ N.C. State | W 30-17 | |
| 2/2/1922 | UNC vs. Wofford | W 54-26 | |
| 2/4/1922 | UNC vs. Duke | W 38-22 | |
| 2/6/1922 | UNC vs. N.C. State | W 49-19 | |
| 2/11/1922 | UNC @ Elon | W 50-24 | |
| 2/14/1922 | UNC vs. Wake Forest | W 42-27 | |
| 2/17/1922 | UNC @ VMI | W 31-26 | |
| 2/18/1922 | UNC @ Washington & Lee | L 25-38 | |
| 2/20/1922 | UNC @ Virginia | L 29-31 | |
| 2/22/1922 | UNC @ Army | L 22-52 | |
| 2/24/1922 | UNC vs. Samford | W 35-21 | Southern Conference Tournament: Atlanta, GA |
| 2/25/1922 | UNC vs. Newberry | W 32-27 | Southern Conference Tournament: Atlanta, GA |
| 2/26/1922 | UNC vs. Georgia | W 33-25 | Southern Conference Tournament: Atlanta, GA |
| 2/27/1922 | UNC vs. Alabama | W 20-11 | Southern Conference Tournament: Atlanta, GA |
| 2/28/1922 | UNC vs. Mercer | W 40-26 | Southern Conference Tournament: Atlanta, GA |
| 3/1/1922 | UNC vs. Washington & Lee | L 36-39 | Memorial Auditorium: Raleigh, NC |
| 3/7/1922 | UNC @ Duke | W 29-23 | |
| | | Record: 15-6 | |