| Date | Game | Result | Notes |
| 11/28/1980 | UNC vs. Alaska | W 69-50 | Great Alaska Shootout - Anchorage, AK |
| 11/29/1980 | UNC vs. Georgetown | W 83-71 | Great Alaska Shootout - Anchorage, AK |
| 11/30/1980 | UNC vs. Arkansas | W 64-58 | Great Alaska Shootout - Anchorage, AK |
| 12/2/1980 | UNC vs. Mercer | W 89-74 | |
| 12/5/1980 | UNC vs. Duke | W 78-76 | Big Four Tournament - Greensboro, NC |
| 12/6/1980 | UNC vs. Wake Forest | L 71-82 | Big Four Tournament - Greensboro, NC |
| 12/13/1980 | UNC vs. South Florida | W 73-64 | Greensboro, NC |
| 12/20/1980 | UNC vs. Indiana | W 65-56 | |
| 12/22/1980 | UNC vs. Rutgers | W 71-64 | Charlotte, NC |
| 12/29/1980 | UNC vs. Louisville | W 86-64 | Winston Tire Classic - Los Angeles, CA |
| 12/30/1980 | UNC vs. Minnesota | L 60-76 | Winston Tire Classic - Los Angeles, CA |
| 1/3/1981 | UNC @ Kansas | L 55-56 | Kansas City, MO |
| 1/7/1981 | UNC vs. Maryland | W 75-66 | |
| 1/10/1981 | UNC @ Virginia | L 57-63 | |
| 1/14/1981 | UNC vs. N.C. State | W 73-70 | |
| 1/17/1981 | UNC vs. Duke | W 80-65 | |
| 1/22/1981 | UNC @ Wake Forest | W 74-60 | |
| 1/24/1981 | UNC vs. Georgia Tech | W 100-60 | |
| 1/28/1981 | UNC @ Clemson | W 61-47 | |
| 1/31/1981 | UNC @ N.C. State | W 57-54 | |
| 2/3/1981 | UNC vs. Virginia | L 79-80 (OT) | |
| 2/6/1981 | UNC vs. St. Joseph's | W 87-64 | North-South Doubleheaders - Charlotte, NC |
| 2/7/1981 | UNC vs. Furman | W 79-64 | North-South Doubleheaders - Charlotte, NC |
| 2/11/1981 | UNC vs. Wake Forest | L 68-84 | |
| 2/15/1981 | UNC @ Maryland | W 76-63 | |
| 2/18/1981 | UNC @ William & Mary | W 81-55 | |
| 2/21/1981 | UNC vs. Clemson | W 75-61 | |
| 2/25/1981 | UNC @ Georgia Tech | W 76-51 | |
| 2/28/1981 | UNC @ Duke | L 65-66 (OT) | |
| 3/5/1981 | UNC vs. N.C. State | W 69-54 | ACC Tournament - Landover, MD |
| 3/6/1981 | UNC vs. Wake Forest | W 58-57 | ACC Tournament - Landover, MD |
| 3/7/1981 | UNC vs. Maryland | W 61-60 | ACC Tournament - Landover, MD |
| 3/15/1981 | UNC vs. Pittsburgh | W 74-57 | NCAA R32 - El Paso, TX |
| 3/19/1981 | UNC vs. Utah | W 61-56 | NCAA R16 - Salt Lake City, UT |
| 3/21/1981 | UNC vs. Kansas State | W 82-68 | NCAA R8 - Salt Lake City, UT |
| 3/28/1981 | UNC vs. Virginia | W 78-65 | NCAA R4 - Philadelphia, PA |
| 3/30/1981 | UNC vs. Indiana | L 50-63 | NCAA R2 - Philadelphia, PA |
| | | Record: 29-8 | |