| Date | Game | |
| 9/2/2006 | vs Rutgers | L 16-21 |
| 9/9/2006 | vs Virginia Tech | L 10-35 |
| 9/16/2006 | vs Furman | W 45-42 |
| 9/23/2006 | at Clemson | L 7-52 |
| 10/7/2006 | at Miami | L 7-27 |
| 10/14/2006 | vs South Florida | L 20-37 |
| 10/19/2006 | at Virginia John Bunting fired 10/20 effective end of season | L 0-23 |
| 10/28/2006 | vs Wake Forest | L 17-24 |
| 11/4/2006 | at Notre Dame Hakeem Nicks sets single-game freshman receiving record with 171 yards | L 26-45 |
| 11/11/2006 | vs Georgia Tech | L 0-7 |
| 11/18/2006 | vs N.C. State | W 23-9 |
| 11/25/2006 | at Duke | W 45-44 |