| Date | Game | |
| Tue Nov 9, 8:00 ET | vs Dartmouth Conte Forum, Chestnut Hill, MA | W 73-57 |
| Fri Nov 12, 7:00 ET | vs Holy Cross Conte Forum, Chestnut Hill, MA | W 85-55 |
| Sun Nov 14, 4:00 ET | vs Fairfield Conte Forum, Chestnut Hill, MA | W 72-64 |
| Wed Nov 17, 6:00 ET | at Rhode Island Thomas M. Ryan Center, Kingston, RI | L 49-57 |
| Sat Nov 20, 5:00 ET | vs Utah Ocean Center, Daytona Beach, FL | L 61-68 |
| Sun Nov 21, 5:00 ET | vs Rhode Island Ocean Center, Daytona Beach, FL | L 65-71 |
| Fri Nov 26, 2:00 ET | vs Columbia Conte Forum, Chestnut Hill, MA | W 73-60 |
| Mon Nov 29, 7:00 ET | vs South Florida Conte Forum, Chestnut Hill, MA | W 64-49 |
| Fri Dec 3, 6:00 ET | vs Notre Dame Conte Forum, Chestnut Hill, MA | W 73-57 |
| Sat Dec 11, 5:00 ET | at Saint Louis Chaifetz Arena, Saint Louis, MO | L 68-79 |
| Mon Dec 13, 8:00 ET | vs Albany Conte Forum, Chestnut Hill, MA | L 57-61 |
| Sun Jan 2, 1:00 ET | vs North Carolina Conte Forum, Chestnut Hill, MA | L 65-91 |
| Sat Jan 8, 4:00 ET | at Pittsburgh Petersen Events Center, Pittsburgh, PA | L 67-69 |
| Wed Jan 12, 9:00 ET | vs Georgia Tech Conte Forum, Chestnut Hill, MA | L 76-81 |
| Sat Jan 15, 6:30 ET | at Clemson Littlejohn Coliseum, Clemson, SC | W 70-68 |
| Wed Jan 19, 7:00 ET | at Louisville KFC Yum Center, Louisville, KY | L 54-67 |
| Sat Jan 22, 12:00 ET | vs Virginia Tech Conte Forum, Chestnut Hill, MA | W 68-63 |
| Mon Jan 24, 6:00 ET | at Wake Forest LJVM Coliseum, Winston-Salem, NC | L 57-87 |
| Wed Jan 26, 7:00 ET | at North Carolina Smith Center, Chapel Hill, NC | L 47-58 |
| Sun Jan 30, 4:00 ET | vs Pittsburgh Conte Forum, Chestnut Hill, MA | W 69-56 |
| Tue Feb 1, 6:00 ET | at Virginia John Paul Jones Arena, Charlottesville, VA | L 55-67 |
| Tue Feb 8, 8:00 ET | vs Syracuse Conte Forum, Chestnut Hill, MA | L 64-73 |
| Sat Feb 12, 5:00 ET | vs Duke Conte Forum, Chestnut Hill, MA | L 61-72 |
| Wed Feb 16, 7:00 ET | at Notre Dame Purcell Pavilion Notre Dame, IN | W 73-57 |
| Wed Feb 16, 7:00 ET | at Notre Dame Purcell Pavilion, Notre Dame, IN | L 95-99 |
| Sat Feb 19, 12:00 ET | at Syracuse Carrier Dome, Syracuse, NY | L 56-76 |
| Mon Feb 21, 7:00 ET | vs Florida State Conte Forum, Chestnut Hill, MA | W 71-55 |
| Wed Feb 23, 7:00 ET | at NC State PNC Arena, Raleigh, NC | W 69-61 |
| Sat Feb 26, 3:00 ET | vs Clemson Conte Forum, Chestnut Hill, MA | L 60-70 |
| Wed Mar 2, 9:00 ET | vs Miami Conte Forum, Chestnut Hill, MA | L 70-81 |
| Sat Mar 5, 12:00 ET | at Georgia Tech McCamish Pavilion, Atlanta, GA | L 78-82 |
| Tue Mar 8, 2:00 ET | vs Pitt Barclays Center, Brooklyn, NY | W 66-46 |
| Wed Mar 9, 2:30 ET | vs Wake Forest Barclays Center, Brooklyn, NY | W 82-77 |
| Thu Mar 10, 2:30 ET | vs Miami Barclays Center, Brooklyn, NY | L 69-71 |