| Date | Game | |
| Tue Nov 3, 7:00 ET | vs Wagner Chestnut, Hill, Mass. | W 76-50 |
| Fri Nov 6, 4:00 ET | vs Massachusetts Boston, Mass. | W 71-55 |
| Tue Nov 10, 7:00 ET | vs Maryland Eastern Shore Chestnut, Hill, Mass. | W 82-54 |
| Sun Nov 15, 1:30 ET | vs New Hampshire | ACCNX |
| Wed Nov 18, 8:00 ET | at Harvard | ESPN+ |
| Sun Nov 22, 5:00 ET | vs NJIT | ACCN |
| Thu Nov 26, 1:30 ET | vs TBA | ESPN2 |
| Fri Nov 27, 4:30 ET | vs TBA | ACCN |
| Tue Dec 1, 5:00 ET | at Georgia | ESPN2 |
| Sat Dec 5, 7:00 ET | vs UMass Lowell Chestnut, Hill, Mass. | ACCN |
| Wed Dec 9, 9:00 ET | vs Northeastern Chestnut, Hill, Mass. | ACCN |
| Sat Dec 12, 12:00 ET | vs George Washington Chestnut, Hill, Mass. | ACCN |
| Sun Dec 20, 12:00 ET | vs New Haven Chestnut, Hill, Mass. | ACCNX |
| Tue Dec 22, 7:00 ET | vs Stonehill Chestnut, Hill, Mass. | ACCNX |
| Sat Jan 2, 4:00 ET | vs North Carolina Chestnut, Hill, Mass. | ESPN/2 |
| Tue Jan 5, 9:00 ET | vs Clemson Chestnut, Hill, Mass. | ACCN |
| Sat Jan 9, 8:00 ET | at Virginia Tech Blacksburg, VA | ACCN |
| Wed Jan 13, 8:00 ET | at Virginia Charlottesville, VA | The CW |
| Sat Jan 16, 7:00 ET | vs Duke Chestnut, Hill, Mass. | ACCN |
| Tue Jan 19, 7:00 ET | at Syracuse Syracuse, NY | ACCN |
| Sat Jan 23, 7:00 ET | at Pittsburgh Pittsburgh, PA | ACCN |
| Wed Jan 27, 7:00 ET | vs Louisville Chestnut, Hill, Mass. | ACCN |
| Tue Feb 2, 6:00 ET | at Wake Forest Winston-Salem, N.C. | ACCN |
| Sat Feb 6, 5:30 ET | vs Notre Dame Chestnut, Hill, Mass. | ACCN |
| Tue Feb 9, 9:00 ET | vs Georgia Tech Chestnut, Hill, Mass. | ACCN |
| Sat Feb 13, 1:00 ET | at NC State Raleigh, NC | The CW |
| Tue Feb 16, 7:00 ET | vs Southern Methodist Chestnut Hill, MA | ACCN |
| Sat Feb 20, 12:00 ET | vs Virginia Tech Chestnut, Hill, Mass. | ACCN |
| Wed Feb 24, 9:00 ET | at California Berkeley, CA | ACCN |
| Sat Feb 27, 8:00 ET | at Stanford Stanford, CA | ESPN2 |
| Wed Mar 3, 6:30 ET | vs Florida State Chestnut Hill, Mass. | ACCN |
| Sat Mar 6, 2:00 ET | at Notre Dame South Bend, Ind. | ACCN |