| Date | Game | |
| Fri Feb 19, 4:00 ET | vs Cincinnati Clemson, S.C. | W 5-0 |
| Sat Feb 20, 3:00 ET | vs Cincinnati Clemson, S.C. | W 5-2 |
| Sun Feb 21, 1:00 ET | vs Cincinnati Clemson, S.C. | W 8-7 |
| Sat Feb 27, 4:00 ET | vs South Carolina Greenville, S.C. | L 2-3 |
| Sun Feb 28, 1:30 ET | at South Carolina Columbia, S.C. | L 7-8 |
| Tue Mar 2, 4:00 ET | vs East Tennessee State Clemson, S.C. | W 7-3 |
| Fri Mar 5, 4:00 ET | vs Notre Dame Clemson, S.C. | W 13-7 |
| Sat Mar 6, 3:00 ET | vs Notre Dame Clemson, S.C. | L 1-3 |
| Sun Mar 7, 1:00 ET | vs Notre Dame Clemson, S.C. | L 2-3 |
| Tue Mar 9, 4:00 ET | vs USC Upstate | L 2-12 |
| Fri Mar 12, 6:00 ET | at North Carolina Chapel Hill, N.C. | L 3-8 |
| Sat Mar 13, 2:00 ET | at North Carolina Chapel Hill, N.C. | L 4-5 |
| Sun Mar 14, 1:00 ET | at North Carolina Chapel Hill, N.C. | L 3-5 |
| Tue Mar 16, 6:00 ET | vs Georgia State Clemson, SC | W 7-2 |
| Fri Mar 19, 6:00 ET | vs Virginia Tech Clemson, S.C. | W 8-2 |
| Sat Mar 20, 3:00 ET | vs Virginia Tech Clemson, S.C. | L 3-11 |
| Sun Mar 21, 1:00 ET | vs Virginia Tech Clemson, S.C. | W 4-2 |
| Tue Mar 23, 6:30 ET | vs Georgia Southern North Augusta, S.C. | W 6-4 |
| Fri Mar 26, 4:00 ET | at Boston College Brighton, Mass. | W 16-12 |
| Sat Mar 27, 1:00 ET | at Boston College Brighton, Mass. | W 9-3 |
| Sat Mar 27, 4:30 ET | at Boston College Brighton, Mass. | W 7-2 |
| Tue Mar 30, 6:00 ET | vs Georgia | L 0-2 |
| Fri Apr 2, 7:00 ET | at NC State Raleigh, N.C. | W 10-6 |
| Sat Apr 3, 7:00 ET | at NC State Raleigh, N.C. | W 9-3 |
| Sun Apr 4, 1:00 ET | at NC State Raleigh, N.C. | L 5-9 |
| Fri Apr 9, 3:00 ET | vs Virginia | W 6-1 |
| Fri Apr 9, 6:00 ET | vs Virginia | |
| Sat Apr 10, 7:00 ET | vs Virginia | L 4-8 |
| Sun Apr 11, 1:00 ET | vs Virginia Clemson, S.C. | L 5-6 |
| Tue Apr 13, 6:00 ET | vs College of Charleston Clemson, SC | L 6-13 |
| Fri Apr 16, 7:00 ET | at Miami | L 3-12 |
| Sat Apr 17, 6:00 ET | at Miami | L 2-10 |
| Sun Apr 18, 12:00 ET | at Miami | L 2-3 |
| Tue Apr 20, 7:00 ET | at Georgia Athens, Ga. | L 7-8 |
| Fri Apr 23, 6:00 ET | vs Wake Forest Clemson, SC | W 5-2 |
| Sat Apr 24, 3:00 ET | vs Wake Forest Clemson, SC | W 6-4 |
| Sun Apr 25, 4:00 ET | vs Wake Forest Clemson, SC | W 3-2 |
| Fri Apr 30, 6:00 ET | vs Louisville Clemson, S.C. | W 11-3 |
| Sat May 1, 3:00 ET | vs Louisville Clemson, S.C. | W 5-4 |
| Sun May 2, 2:00 ET | vs Louisville Clemson, S.C. | W 15-5 |
| Wed May 5, 6:00 ET | vs USC Upstate Athens, Ga. | W 9-2 |
| Fri May 7, 6:00 ET | at Georgia Tech | L 1-6 |
| Sat May 8, 4:00 ET | at Georgia Tech | L 5-6 |
| Sun May 9, 1:00 ET | at Georgia Tech | L 8-9 |
| Tue May 11, 6:00 ET | vs South Carolina Clemson, S.C. | W 7-2 |
| Fri May 14, 6:00 ET | at Florida State Tallahassee, Fla. | L 3-8 |
| Sat May 15, 2:00 ET | at Florida State Tallahassee, Fla. | W 9-5 |
| Sun May 16, 1:00 ET | at Florida State Tallahassee, Fla. | L 6-9 |
| Thu May 20, 6:00 ET | vs Duke Clemson, S.C. | L 1-5 |
| Fri May 21, 6:00 ET | vs Duke Clemson, S.C. | L 8-14 |
| Sat May 22, 1:00 ET | vs Duke Clemson, S.C. | L 2-4 |
| Tue May 25, 11:00 AM ET | vs Louisville Charlotte, NC | L 10-15 |
| Wed May 26, 7:00 ET | vs Georgia Tech Charlotte, NC | W 11-5 |