| Date | Game | |
| Fri Feb 14, 12:00 ET | vs Oklahoma State Arlington, Texas | W 6-5 |
| Sat Feb 15, 12:00 ET | vs Arizona Arlington, Texas | W 16-5 |
| Sun Feb 16, 3:30 ET | vs Ole Miss Arlington, Texas | L 5-15 |
| Fri Feb 21, 4:00 ET | vs VCU Clemson, S.C. | W 6-2 |
| Sat Feb 22, 12:00 ET | vs North Carolina A&T Clemson, S.C. | W 12-7 |
| Sat Feb 22, 4:00 ET | vs VCU Clemson, S.C. | W 4-3 |
| Sun Feb 23, 2:00 ET | vs North Carolina A&T Clemson, S.C. | W 4-2 |
| Tue Feb 25, 4:00 ET | vs Winthrop Clemson, S.C. | W 20-7 |
| Fri Feb 28, 7:00 ET | vs South Carolina Clemson, S.C. | W 5-3 |
| Sat Mar 1, 1:30 ET | vs South Carolina Greenville,S.C. | W 5-1 |
| Sun Mar 2, 5:00 ET | at South Carolina Columbia, S.C. | W 8-2 |
| Tue Mar 4, 6:00 ET | vs USC Upstate Greenville, S.C. | W 7-0 |
| Wed Mar 5, 4:00 ET | vs Presbyterian Clemson, S.C. | W 11-2 |
| Fri Mar 7, 4:00 ET | vs Davidson Clemson, S.C. | W 7-4 |
| Sat Mar 8, 3:00 ET | vs Davidson Clemson, S.C. | W 14-4 |
| Sun Mar 9, 2:00 ET | vs Davidson Clemson, S.C. | W 11-4 |
| Tue Mar 11, 6:00 ET | vs Liberty Clemson, S.C. | W 6-4 |
| Wed Mar 12, 4:00 ET | vs Liberty Clemson, S.C. | W 8-2 |
| Fri Mar 14, 4:00 ET | vs Notre Dame Clemson, S.C. | W 2-1 |
| Sat Mar 15, 3:00 ET | vs Notre Dame Clemson, S.C. | W 11-7 |
| Sun Mar 16, 12:00 ET | vs Notre Dame Clemson, S.C. | L 3-7 |
| Tue Mar 18, 6:00 ET | vs The Citadel Clemson, S.C. | W 6-4 |
| Wed Mar 19, 6:00 ET | vs The Citadel Clemson, S.C. | W 11-1 |
| Fri Mar 21, 6:00 ET | vs Wake Forest Clemson, S.C. | W 5-1 |
| Sat Mar 22, 2:00 ET | vs Wake Forest Clemson, S.C. | L 10-12 |
| Sun Mar 23, 3:00 ET | vs Wake Forest Clemson, S.C. | W 7-6 |
| Tue Mar 25, 6:00 ET | vs Coastal Carolina Clemson, S.C. | L 2-8 |
| Wed Mar 26, 6:00 ET | vs Presbyterian Clemson, S.C. | W 9-1 |
| Fri Mar 28, 6:00 ET | at Georgia Tech Atlanta, Ga. | W 9-7 |
| Sat Mar 29, 4:00 ET | at Georgia Tech Atlanta, Ga. | L 2-18 |
| Sun Mar 30, 1:00 ET | at Georgia Tech Atlanta, Ga. | W 4-3 |
| Tue Apr 1, 6:30 ET | vs Georgia Southern North Augusta, S.C. | W 10-8 |
| Fri Apr 4, 9:00 ET | at California Berkeley, Calif. | W 6-4 |
| Sat Apr 5, 5:00 ET | at California Berkeley, Calif. | W 13-3 |
| Sun Apr 6, 4:00 ET | at California Berkeley, Calif. | W 4-3 |
| Wed Apr 9, 7:00 ET | vs Gardner-Webb Clemson, S.C. | W 4-2 |
| Fri Apr 11, 6:00 ET | vs Stanford Clemson, S.C. | W 11-1 |
| Sat Apr 12, 6:00 ET | vs Stanford Clemson, S.C. | W 11-10 |
| Sun Apr 13, 3:00 ET | vs Stanford Clemson, S.C. | L 6-11 |
| Thu Apr 17, 7:00 ET | vs Louisville Clemson, S.C. | W 7-6 |
| Fri Apr 18, 5:00 ET | vs Louisville Clemson, S.C. | W 2-1 |
| Sat Apr 19, 1:00 ET | vs Louisville Clemson, S.C. | L 6-8 |
| Tue Apr 22, 8:00 ET | vs Georgia Clemson, S.C. | W 3-0 |
| Thu Apr 24, 7:00 ET | at NC State Raleigh, N.C. | L 4-14 |
| Fri Apr 25, 6:00 ET | at NC State Raleigh, N.C. | L 3-8 |
| Sat Apr 26, 1:00 ET | at NC State Raleigh, N.C. | L 1-4 |
| Fri May 2, 6:00 ET | at Florida State Tallahassee, Fla. | L 5-6 |
| Sat May 3, 6:00 ET | at Florida State Tallahassee, Fla. | W 6-3 |
| Sun May 4, 1:00 ET | at Florida State Tallahassee, Fla. | L 9-20 |
| Tue May 6, 6:00 ET | at Coastal Carolina Conway, S.C. | L 3-5 |
| Fri May 9, 6:00 ET | vs Duke Clemson, S.C. | W 9-7 |
| Sat May 10, 2:00 ET | vs Duke Clemson, S.C. | L 10-15 |
| Sun May 11, 1:00 ET | vs Duke Clemson, S.C. | L 4-8 |
| Thu May 15, 6:00 ET | at Pitt Pittsburgh, Pa. | W 6-1 |
| Fri May 16, 3:00 ET | at Pitt Pittsburgh, Pa. | W 11-2 |
| Sat May 17, 1:00 ET | at Pitt Pittsburgh, Pa. | W 13-6 |
| Wed May 21, 1:00 ET | vs Virginia Tech Durham, N.C. (ACC Championship) | W 6-1 |
| Thu May 22, 7:00 ET | vs NC State Durham, N.C. (ACC Championship) | W 7-6 |
| Sat May 24, 1:00 ET | vs Georgia Tech Durham, N.C. (ACC Championship) | W 9-4 |
| Sun May 25, 12:00 ET | vs North Carolina Durham, N.C. (ACC Championship) | L 4-14 |
| Fri May 30, 6:00 ET | vs USC Upstate Clemson, S.C. | W 7-3 |
| Sat May 31, 6:00 ET | vs West Virginia Clemson, S.C. | L 6-9 |
| Sun Jun 1, 12:00 ET | vs Kentucky Clemson, S.C. | L 4-16 |