| Date | Game | |
| Sat Aug 30, 7:30 ET | vs LSU Clemson, S.C. | L 10-17 |
| Sat Sep 6, 3:30 ET | vs Troy Clemson, S.C. | W 27-16 |
| Sat Sep 13, 12:00 ET | at Georgia Tech Atlanta, Ga. | L 21-24 |
| Sat Sep 20, 12:00 ET | vs Syracuse Clemson, S.C. | ESPN |
| Sat Oct 4 | at North Carolina Chapel Hill, N.C. | |
| Sat Oct 11 | at Boston College Chestnut Hill, Mass. | |
| Sat Oct 18 | vs SMU Clemson, S.C. | |
| Sat Nov 1 | vs Duke Clemson, S.C. | |
| Sat Nov 8 | vs Florida State Clemson, S.C. | |
| Fri Nov 14, 7:30 ET | at Louisville Louisville, Ky. | ESPN |
| Sat Nov 22 | vs Furman Clemson, S.C. | |
| Sat Nov 29, 12:00 ET | at South Carolina Columbia, S.C. | ABC or ESPN |