| Date | Game | |
| Mon Nov 7, 7:00 ET | vs The Citadel Clemson, SC | W 80-69 |
| Fri Nov 11, 7:00 ET | at South Carolina Columbia, SC | L 58-60 |
| Tue Nov 15, 7:00 ET | vs USC Upstate Clemson, SC | W 81-70 |
| Fri Nov 18, 7:00 ET | vs Bellarmine Clemson, SC | W 76-66 |
| Mon Nov 21, 7:00 ET | vs Loyola, Maryland Clemson, SC | W 72-41 |
| Fri Nov 25, 6:00 ET | vs Iowa Niceville, FL | L 71-74 |
| Sat Nov 26, 5:00 ET | vs California Niceville, FL | W 67-59 |
| Tue Nov 29, 7:00 ET | vs Penn State Clemson, SC | W 101-94 |
| Fri Dec 2, 7:00 ET | vs Wake Forest Clemson, SC | W 77-57 |
| Wed Dec 7, 9:00 ET | vs Towson Clemson, SC | W 80-75 |
| Sat Dec 10, 7:30 ET | vs Loyola Chicago Atlanta, GA | L 58-76 |
| Sat Dec 17, 7:00 ET | vs Richmond Greenville, SC | W 85-57 |
| Wed Dec 21, 7:30 ET | at Georgia Tech Atlanta, Ga. | W 79-66 |
| Fri Dec 30, 4:00 ET | vs NC State Clemson, SC | W 78-64 |
| Wed Jan 4, 9:00 ET | at Virginia Tech Blacksburg, Va. | W 68-65 |
| Sat Jan 7, 4:00 ET | at Pitt Pittsburgh, PA | W 75-74 |
| Wed Jan 11, 9:00 ET | vs Louisville Clemson, SC | W 83-70 |
| Sat Jan 14, 5:00 ET | vs Duke Clemson, SC | W 72-64 |
| Tue Jan 17, 9:00 ET | at Wake Forest Winston-Salem, N.C. | L 77-87 |
| Sat Jan 21, 6:00 ET | vs Virginia Tech Clemson, SC | W 51-50 |
| Tue Jan 24, 9:00 ET | vs Georgia Tech Clemson, SC | W 72-51 |
| Sat Jan 28, 5:00 ET | at Florida State Tallahassee, FL | W 82-81 |
| Tue Jan 31, 7:00 ET | at Boston College Chestnut Hill, Mass. | L 54-62 |
| Sat Feb 4, 3:00 ET | vs Miami Clemson, SC | L 74-78 |
| Sat Feb 11, 2:00 ET | at North Carolina Chapel Hill, NC | L 71-91 |
| Wed Feb 15, 7:00 ET | vs Florida State Clemson, SC | W 94-54 |
| Sat Feb 18, 7:00 ET | at Louisville Louisville, KY | L 73-83 |
| Wed Feb 22, 7:00 ET | vs Syracuse Clemson, SC | W 91-73 |
| Sat Feb 25, 12:00 ET | at NC State Raleigh, NC | W 96-71 |
| Tue Feb 28, 7:00 ET | at Virginia Charlottesville, VA | L 57-64 |
| Sat Mar 4, 8:00 ET | vs Notre Dame Clemson, SC | W 87-64 |
| Thu Mar 9, 9:30 ET | vs NC State Greensboro, N.C. | W 80-54 |
| Fri Mar 10, 9:30 ET | vs Virginia Greensboro, N.C. | L 56-76 |
| Wed Mar 15, 7:00 ET | vs Morehead State Clemson, SC / NIT | L 64-68 |