| Date | Game | |
| Mon Nov 6, 7:00 ET | vs Winthrop Clemson, SC | W 78-56 |
| Fri Nov 10, 9:30 ET | vs UAB Asheville, N.C. | W 77-76 |
| Sun Nov 12, 3:00 ET | vs Davidson Asheville, N.C. | W 68-65 |
| Sun Nov 19, 1:00 ET | vs Boise State Clemson, SC | W 85-68 |
| Fri Nov 24, 8:00 ET | vs Alcorn State Clemson, SC | W 90-69 |
| Tue Nov 28, 9:30 ET | at Alabama Tuscaloosa, AL | W 85-77 |
| Sun Dec 3, 2:00 ET | at Pitt Pittsburgh, Pa. | W 79-70 |
| Wed Dec 6, 8:00 ET | vs South Carolina Clemson, SC | W 72-67 |
| Sat Dec 9, 4:00 ET | vs TCU Toronto, Ontario | W 74-66 |
| Sat Dec 16, 3:00 ET | at Memphis Memphis, TN | L 77-79 |
| Fri Dec 22, 6:00 ET | vs Queens Clemson, SC | W 109-79 |
| Fri Dec 29, 7:00 ET | vs Radford Clemson, SC | W 93-58 |
| Wed Jan 3, 8:00 ET | at Miami Coral Gables, FL | L 82-95 |
| Sat Jan 6, 12:00 ET | vs North Carolina Clemson, S.C. | L 55-65 |
| Wed Jan 10, 7:00 ET | at Virginia Tech Blacksburg, Va. | L 72-87 |
| Sat Jan 13, 3:00 ET | vs Boston College Clemson, SC | W 89-78 |
| Tue Jan 16, 9:00 ET | vs Georgia Tech Clemson, SC | L 90-93 |
| Sat Jan 20, 4:00 ET | at Florida State Tallahassee, Fla. | W 78-67 |
| Sat Jan 27, 4:00 ET | at Duke Durham, N.C. | L 71-72 |
| Tue Jan 30, 9:00 ET | vs Louisville Clemson, SC | W 70-64 |
| Sat Feb 3, 2:00 ET | vs Virginia Clemson, SC | L 65-66 |
| Tue Feb 6, 7:00 ET | at North Carolina Chapel Hill, NC | W 80-76 |
| Sat Feb 10, 12:00 ET | at Syracuse Syracuse, N.Y. | W 77-68 |
| Wed Feb 14, 7:00 ET | vs Miami Clemson, SC | W 77-60 |
| Sat Feb 17, 7:45 ET | vs NC State Clemson, SC | L 77-78 |
| Wed Feb 21, 7:00 ET | at Georgia Tech Atlanta, GA | W 81-57 |
| Sat Feb 24, 7:45 ET | vs Florida State Clemson, SC | W 74-63 |
| Tue Feb 27, 7:00 ET | vs Pitt Clemson, SC | W 69-62 |
| Sat Mar 2, 7:45 ET | at Notre Dame Notre Dame, IN | L 62-69 |
| Tue Mar 5, 7:00 ET | vs Syracuse Clemson, SC | W 90-75 |
| Sat Mar 9, 6:00 ET | at Wake Forest Winston-Salem, N.C. | L 76-81 |
| Wed Mar 13, 9:30 ET | vs Boston College Washington, D.C. | L 55-76 |
| Fri Mar 22, 3:10 ET | vs New Mexico Memphis, TN | W 77-56 |
| Sun Mar 24, 6:10 ET | vs Baylor Memphis, TN | W 72-64 |
| Thu Mar 28, 7:09 ET | vs Arizona Los Angeles, CA | W 77-72 |
| Sat Mar 30, 8:49 ET | vs Alabama Los Angeles, CA | L 82-89 |