| Date | Game | |
| Thu Aug 24, 7:00 ET | vs UCF Clemson, SC | L 1-2 |
| Mon Aug 28, 7:00 ET | vs UNCW Clemson, SC | T 1-1 |
| Fri Sep 1, 7:00 ET | vs South Carolina Clemson, SC | W 2-0 |
| Tue Sep 5, 7:00 ET | vs Presbyterian Clemson, SC | W 6-0 |
| Sat Sep 9, 7:00 ET | at Notre Dame South Bend, Ind. | L 2-3 |
| Tue Sep 12, 7:00 ET | at South Florida Tampa, FL | W 3-2 |
| Fri Sep 15, 7:30 ET | vs Duke Clemson, S.C. | W 2-0 |
| Tue Sep 19, 7:00 ET | vs Gardner-Webb Clemson, SC | W 7-0 |
| Fri Sep 22, 6:00 ET | at Wake Forest Winston-Salem, N.C. | L 0-1 |
| Fri Sep 29, 7:00 ET | vs Virginia Tech Clemson, S.C. | W 2-1 |
| Tue Oct 3, 7:00 ET | vs Winthrop Clemson, SC | W 4-1 |
| Fri Oct 6, 7:00 ET | vs Louisville Clemson, S.C. | W 4-0 |
| Sun Oct 15, 1:00 ET | at Syracuse Syracuse, NY | T 1-1 |
| Fri Oct 20, 6:00 ET | vs Boston College Clemson, SC | W 6-0 |
| Fri Oct 27, 7:00 ET | at NC State Raleigh, NC | T 1-1 |
| Sun Nov 5, 6:00 ET | vs Duke Clemson, SC | T 3-3 |
| Wed Nov 8, 8:00 ET | vs Louisville Clemson, SC | W 5-1 |
| Sun Nov 12, 12:00 ET | vs North Carolina Cary, NC | T 1-1 |
| Sun Nov 19, 6:30 ET | vs Charlotte Clemson, SC | W 3-0 |
| Sun Nov 26, 5:00 ET | at New Hampshire Durham, NH | W 1-0 |
| Sat Dec 2, 6:00 ET | vs Stanford Clemson, SC | W 2-0 |
| Fri Dec 8, 6:00 ET | vs West Virginia Louisville, KY | W 1-0 |
| Mon Dec 11, 6:00 ET | vs Notre Dame Louisville, KY | W 2-1 |