| Date | Game | |
| Thu Aug 22, 7:00 ET | vs Penn State Clemson, SC | W 3-0 |
| Fri Aug 30, 7:00 ET | at South Carolina Columbia, SC | T 2-2 |
| Fri Sep 6, 7:00 ET | vs Stanford Clemson, SC | L 2-3 |
| Tue Sep 10, 7:00 ET | vs Loyola Maryland Clemson, SC | W 6-0 |
| Fri Sep 13, 7:00 ET | at Boston College Newton, MA | W 1-0 |
| Mon Sep 16, 7:00 ET | at Holy Cross Worcester, MA | T 2-2 |
| Fri Sep 20, 7:30 ET | vs Wake Forest Clemson, S.C. | W 1-0 |
| Tue Sep 24, 7:00 ET | vs Liberty Clemson, SC | W 1-0 |
| Fri Sep 27, 7:30 ET | at Notre Dame South Bend, Ind. | L 1-2 |
| Fri Oct 4, 7:00 ET | vs North Carolina Clemson, S.C. | W 3-2 |
| Fri Oct 11, 8:00 ET | at Louisville Louisville, Ky. | W 3-2 |
| Tue Oct 15, 7:00 ET | vs Queens Clemson, SC | W 4-2 |
| Tue Oct 22, 7:00 ET | vs USC Upstate Clemson, SC | W 6-0 |
| Fri Oct 25, 8:00 ET | vs Syracuse Clemson, SC | W 6-1 |
| Tue Oct 29, 7:00 ET | vs Wofford Clemson, SC | W 2-1 |
| Fri Nov 1, 6:00 ET | at Virginia Tech Blacksburg, VA | T 2-2 |
| Wed Nov 6, 6:00 ET | vs Louisville Clemson, SC | W 3-1 |
| Sun Nov 10, 2:00 ET | vs Stanford Clemson, SC | W 1-0 |
| Thu Nov 14, 8:00 ET | vs California Cary, NC | W 3-2 |
| Sun Nov 17, 12:00 ET | vs Wake Forest Cary, NC | T 1-1 |
| Sun Nov 24, 6:00 ET | vs Providence Clemson, SC | W 2-0 |
| Sun Dec 1, 6:00 ET | at Wake Forest Winston-Salem, NC | L 1-2 |