| Date | Game | |
| Thu Aug 20, 8:00 ET | vs Furman Clemson, SC | W 5-1 |
| Sun Aug 23, 7:00 ET | vs ETSU Clemson, SC | W 2-0 |
| Fri Aug 28, 7:00 ET | at South Carolina Columbia, SC | L 2-3 |
| Tue Sep 1, 7:00 ET | at UCF Orlando, FL | W 4-1 |
| Fri Sep 4, 7:00 ET | at Syracuse Syracuse, NY | W 1-0 |
| Fri Sep 11, 7:00 ET | vs Notre Dame Clemson, SC | ACCNX |
| Tue Sep 15, 7:00 ET | vs North Florida Clemson, SC | ACCNX |
| Sat Sep 19, 7:00 ET | at North Carolina Chapel Hill | ACCNX |
| Fri Sep 25, 7:00 ET | vs Boston College Clemson, S.C. | ACCNX |
| Tue Sep 29, 7:00 ET | vs Wofford Clemson, SC | ACCNX |
| Fri Oct 2, 7:00 ET | vs UNCW Clemson, SC | ACCNX |
| Tue Oct 6, 7:00 ET | vs Georgia Southern Clemson, SC | ACCNX |
| Sun Oct 11, 9:00 ET | at Stanford Stanford, CA | ACCNX |
| Fri Oct 16, 7:30 ET | vs Louisville Clemson, SC | ACCN |
| Sun Oct 25, 2:00 ET | at Virginia Tech Blacksburg, VA | ESPNU |
| Fri Oct 30, 7:00 ET | vs Wake Forest Clemson, S.C. | ACCNX |