| Date | Game | |
| Sun Jan 15, 3:00 ET | vs Furman University Clemson, SC | W 7-0 |
| Sun Jan 15, 3:00 ET | vs Wofford Clemson, SC | W 6-1 |
| Sat Jan 21, 11:00 AM ET | vs East Tennessee State University Clemson, SC | W 7-0 |
| Sat Jan 21, 3:00 ET | vs The Citadel Clemson, SC | W 7-0 |
| Fri Jan 27, 3:00 ET | vs South Alabama Clemson, SC | W 5-2 |
| Sun Jan 29, 12:00 ET | vs Nebraska Clemson, SC | W 4-0 |
| Fri Feb 3, 5:00 ET | vs University of South Carolina Clemson, SC | L 0-7 |
| Fri Feb 10, 5:00 ET | at Liberty Lynchburg, VA | W 5-2 |
| Sat Feb 11, 2:00 ET | vs VCU Lynchburg, Va. (Liberty) | L 0-4 |
| Fri Feb 17, 2:00 ET | vs FAU | W 4-2 |
| Sun Feb 19, 12:00 ET | vs Northwestern University Clemson, SC | L 3-4 |
| Sat Feb 25, 12:00 ET | vs University of North Carolina Wilmington Clemson, SC | W 4-1 |
| Fri Mar 3, 5:00 ET | vs NC State Clemson, SC | L 0-4 |
| Sun Mar 5, 12:00 ET | vs Wake Forest Clemson, SC | L 1-6 |
| Wed Mar 15, 5:00 ET | vs Georgia Tech Clemson, SC | L 1-4 |
| Fri Mar 17, 3:00 ET | at Boston College Weymouth, MA | W 5-2 |
| Fri Mar 24, 12:00 ET | vs Duke Clemson, SC | L 0-7 |
| Sun Mar 26, 12:00 ET | vs North Carolina Clemson, SC | L 1-4 |
| Fri Mar 31, 3:00 ET | at Miami Coral Gables, FL | L 0-7 |
| Sun Apr 2, 12:00 ET | at Florida State Tallahassee, FL | L 0-4 |
| Fri Apr 7, 5:00 ET | vs Notre Dame Clemson, SC | L 3-4 |
| Sun Apr 9 | vs Louisville Clemson, SC | L 2-4 |
| Fri Apr 14, 5:00 ET | at Virginia Charlottesville, VA | L 1-4 |
| Sun Apr 16, 12:30 ET | at Virginia Tech Blacksburg, VA | L 1-4 |
| Wed Apr 19, 3:30 ET | vs Boston College Cary, NC | W 4-1 |
| Thu Apr 20, 3:30 ET | vs Florida State Cary, NC | L 0-4 |