| Date | Game | |
| Thu Feb 8, 7:00 ET | vs Missouri State Clearwater, Fla | W 12-0 |
| Fri Feb 9, 7:00 ET | vs Indiana Clearwater, Fla | W 3-2 |
| Sat Feb 10, 12:00 ET | vs Liberty Clearwater, Fla | W 7-3 |
| Sat Feb 10, 7:00 ET | vs Oregon Clearwater, Fla | W 3-2 |
| Sun Feb 11, 10:00 AM ET | vs Missouri Clearwater, Fla | L 1-4 |
| Wed Feb 14, 1:00 ET | vs Wichita State Puerto Vallarta, Mexico | W 7-0 |
| Wed Feb 14, 2:30 ET | vs UC San Diego Puerto Vallarta, Mexico | W 6-4 |
| Sat Feb 17, 9:30 ET | vs Mississippi State Puerto Vallarta, Mexico | L 3-6 |
| Wed Feb 21, 4:00 ET | at Charlotte Charlotte, N.C. | W 8-5 |
| Fri Feb 23, 4:00 ET | vs Ole Miss Clemson, S.C. | W 9-1 |
| Sat Feb 24, 1:30 ET | vs Miami Clemson, SC | W 10-1 |
| Sat Feb 24, 4:00 ET | vs Uconn Clemson, S.C. | W 3-2 |
| Sun Feb 25 | vs University of Mississippi Clemson, S.C. | W 5-0 |
| Wed Feb 28, 5:00 ET | vs University of Georgia Clemson, SC | L 1-2 |
| Sat Mar 2, 1:00 ET | vs NC State Clemson, SC | L 1-6 |
| Sat Mar 2, 3:00 ET | vs NC State Clemson, SC | W 8-0 |
| Sun Mar 3, 12:00 ET | vs NC State Clemson, SC | W 14-9 |
| Tue Mar 5, 6:00 ET | vs Tennessee Clemson, S.C. | L 1-2 |
| Thu Mar 7, 4:00 ET | vs Minnesota Clemson, S.C. | L 3-5 |
| Thu Mar 7, 6:00 ET | vs Minnesota Clemson, S.C. | W 3-1 |
| Fri Mar 8, 6:00 ET | vs Mercer Clemson, S.C. | W 7-2 |
| Sat Mar 9, 6:00 ET | vs Longwood Clemson, S.C. | W 9-1 |
| Sun Mar 10, 12:30 ET | vs Fordham Clemson, S.C. | W 12-0 |
| Wed Mar 13, 6:00 ET | vs Gardner-Webb Clemson, S.C. | W 8-0 |
| Fri Mar 15, 6:00 ET | vs North Carolina Clemson, S.C. | W 5-0 |
| Sat Mar 16, 1:00 ET | vs North Carolina Clemson, S.C. | W 4-1 |
| Sun Mar 17, 7:00 ET | vs North Carolina Clemson, S.C. | W 9-1 |
| Wed Mar 20, 6:00 ET | vs South Carolina Clemson, S.C. | L 4-6 |
| Fri Mar 22, 6:00 ET | at Virginia Charlottesville, VA | L 4-6 |
| Sat Mar 23, 1:00 ET | at Virginia Charlottesville, VA | W 5-1 |
| Sun Mar 24, 7:00 ET | at Virginia Charlottesville, VA | L 0-3 |
| Thu Mar 28, 5:00 ET | vs Boston College Clemson, S.C. | W 10-2 |
| Fri Mar 29, 6:00 ET | vs Boston College Clemson, S.C. | L 0-4 |
| Sat Mar 30, 11:00 AM ET | vs Boston College Clemson, S.C. | W 10-0 |
| Tue Apr 2, 6:00 ET | vs Furman Clemson, S.C. | L 3-4 |
| Sat Apr 6, 4:00 ET | at Syracuse Syracuse, N.Y. | W 13-2 |
| Sun Apr 7, 10:00 AM ET | at Syracuse Syracuse, N.Y. | W 10-1 |
| Sun Apr 7, 12:00 ET | at Syracuse Syracuse, N.Y. | W 7-1 |
| Tue Apr 9, 7:00 ET | at South Carolina Columbia, S.C. | W 7-0 |
| Fri Apr 12, 7:00 ET | vs Duke Clemson, S.C. | L 9-13 |
| Sat Apr 13, 1:00 ET | vs Duke Clemson, S.C. | L 3-4 |
| Sun Apr 14, 6:00 ET | vs Duke Clemson, S.C. | L 1-6 |
| Tue Apr 16, 7:00 ET | vs Winthrop Clemson, S.C. | W 4-0 |
| Fri Apr 19, 5:00 ET | at Notre Dame Notre Dame, Ind. | W 8-5 |
| Sat Apr 20, 1:00 ET | at Notre Dame Notre Dame, Ind. | W 11-6 |
| Sun Apr 21, 6:00 ET | at Notre Dame Notre Dame, Ind. | L 5-6 |
| Fri Apr 26, 6:00 ET | at Louisville LOUISVILLE, Ky. | W 6-5 |
| Sat Apr 27, 1:00 ET | at Louisville LOUISVILLE, Ky. | L 3-6 |
| Sun Apr 28, 12:00 ET | at Louisville LOUISVILLE, Ky. | W 11-5 |
| Thu May 9, 1:30 ET | vs Virginia Durham, N.C. | W 8-1 |
| Fri May 10, 1:00 ET | at Duke Durham, NC | L 3-4 |
| Fri May 17, 2:00 ET | vs Southeastern Louisiana Tuscaloosa, Ala. | L 2-6 |
| Sat May 18, 2:00 ET | vs USC Upstate Tuscaloosa, Ala. | |