| Date | Game | |
| Mon Nov 7, 11:00 AM ET | vs Gardner Webb Clemson, SC | W 81-54 |
| Thu Nov 10, 7:00 ET | vs Wofford Clemson, SC | W 79-68 |
| Sun Nov 13, 2:00 ET | vs Richmond Clemson, SC | W 61-40 |
| Thu Nov 17, 6:00 ET | vs South Carolina Clemson, SC | L 31-85 |
| Thu Nov 24, 9:00 ET | vs Kansas State St. Thomas, USVI | L 38-76 |
| Fri Nov 25, 9:00 ET | vs Arkansas St. Thomas, USVI | L 62-76 |
| Sat Nov 26, 5:45 ET | vs Northern Arizona St. Thomas, USVI | W 80-62 |
| Thu Dec 1, 6:00 ET | at Charleston Southern Charleston, SC | W 84-31 |
| Sun Dec 4, 2:00 ET | at Georgia State Atlanta, Ga. | W 85-58 |
| Thu Dec 8, 7:00 ET | vs Charlotte Clemson, SC | W 79-54 |
| Sat Dec 10, 2:00 ET | vs Western Carolina Clemson, SC | W 81-42 |
| Sun Dec 18, 6:00 ET | at NC State Raleigh, N.C. | L 59-77 |
| Tue Dec 20, 1:00 ET | vs Radford Clemson, SC | W 81-38 |
| Thu Dec 29, 6:00 ET | vs Virginia Tech Clemson, SC | W 64-59 |
| Sun Jan 1, 2:00 ET | vs Wake Forest Clemson, SC | W 60-59 |
| Thu Jan 5, 6:00 ET | at Florida State Tallahassee, FL | L 62-93 |
| Sun Jan 8, 2:00 ET | vs Syracuse Clemson, SC | L 77-91 |
| Thu Jan 12, 7:00 ET | at Duke Durham, N.C. | L 56-66 |
| Sun Jan 15, 2:00 ET | at Pitt Pittsburgh, Pa. | W 72-57 |
| Thu Jan 19, 7:00 ET | vs Notre Dame Clemson, SC | L 54-57 |
| Sun Jan 22, 2:00 ET | at Boston College Chestnut Hill, MA | W 67-57 |
| Thu Jan 26, 7:00 ET | at Georgia Tech Atlanta, GA | L 74-85 |
| Sun Jan 29, 4:00 ET | vs North Carolina Clemson, SC | L 58-69 |
| Thu Feb 2, 8:00 ET | vs Miami Clemson, SC | L 66-69 |
| Sun Feb 5, 4:00 ET | at Wake Forest Winston-Salem, N.C. | L 64-69 |
| Thu Feb 9, 8:00 ET | vs Georgia Tech Clemson, SC | W 57-41 |
| Sun Feb 12, 2:00 ET | at Louisville Louisville, KY | L 69-81 |
| Thu Feb 16, 6:00 ET | at Miami Coral Gables, FL | L 54-59 |
| Thu Feb 23, 7:00 ET | vs Virginia Clemson, SC | W 79-69 |
| Sun Feb 26, 2:00 ET | vs Florida State Clemson, SC | W 74-61 |
| Wed Mar 1, 3:30 ET | vs Pitt Greensboro, N.C. | W 71-53 |
| Thu Mar 2, 6:00 ET | vs North Carolina Greensboro, N.C. | L 58-68 |
| Thu Mar 16, 7:00 ET | vs High Point Clemson, SC | W 66-46 |
| Mon Mar 20, 7:00 ET | vs Auburn Clemson, SC | W 56-55 |
| Thu Mar 23, 7:00 ET | vs Florida Clemson, SC | L 63-73 |