| Date | Game | |
| Sat Feb 7, 12:00 ET | vs Vanderbilt Clemson, SC | W 20-5 |
| Tue Feb 10, 6:00 ET | vs Furman Clemson, SC | W 18-1 |
| Sat Feb 14, 12:00 ET | vs Stanford Clemson, SC | L 9-10 |
| Tue Feb 17, 4:00 ET | at Queens Charlotte, NC | ESPN+ |
| Sat Feb 21, 1:00 ET | vs Florida Milton, GA | |
| Sat Feb 28, 2:00 ET | at Boston College Chestnut Hill, Mass. | ACCNX |
| Wed Mar 4, 6:00 ET | vs North Carolina Clemson, S.C. | ACCNX |
| Sun Mar 8, 1:30 ET | vs Notre Dame Clemson, SC | ACCNX |
| Sat Mar 14, 4:00 ET | at Virginia Charlottesville, VA | ACCN |
| Tue Mar 17, 4:00 ET | at Mercer Macon, GA | |
| Sat Mar 21, 1:00 ET | at Pitt Pittsburgh, PA | ACCNX |
| Mon Mar 23, 6:00 ET | vs Wofford Clemson, SC | ACCNX |
| Sat Mar 28, 7:00 ET | vs Virginia Tech Clemson, SC | ACCNX |
| Tue Mar 31, 5:00 ET | vs Davidson Clemson, SC | ACCNX |
| Fri Apr 3, 6:00 ET | at California Berkeley, CA | ACCNX |
| Sat Apr 11, 12:00 ET | vs Duke Clemson, SC | ACCN |
| Thu Apr 16, 2:00 ET | at Florida State Tallahassee, FL | ACCNX |