| Date | Game | |
| Thu Aug 19, 7:00 ET | vs Saint Francis Clemson, SC | W 8-0 |
| Sun Aug 22, 7:00 ET | vs Loyola Clemson, SC | W 4-0 |
| Sat Aug 28, 8:00 ET | at Texas A&M College Station, TX | L 1-3 |
| Thu Sep 2, 7:00 ET | at Georgia Athens, Ga. | L 1-3 |
| Sun Sep 5, 2:00 ET | vs College of Charleston Athens, Ga. | W 8-0 |
| Thu Sep 9, 6:00 ET | vs South Carolina Clemson, SC | W 2-1 |
| Sun Sep 12, 6:00 ET | at Gardner-Webb Boiling Springs, N.C. | W 4-0 |
| Thu Sep 16, 8:00 ET | vs Pitt Clemson, S.C. | W 2-0 |
| Thu Sep 23, 7:00 ET | at NC State Raleigh, N.C. | W 2-1 |
| Sun Sep 26, 1:00 ET | at North Carolina Chapel Hill, N.C. | L 0-3 |
| Fri Oct 1, 7:00 ET | vs Florida State Clemson, SC | L 1-4 |
| Thu Oct 7, 8:00 ET | vs Virginia Tech Clemson, SC | W 1-0 |
| Sun Oct 10, 3:00 ET | at Notre Dame South Bend, Ind. | L 1-2 |
| Sat Oct 16, 7:00 ET | at Miami Coral Gables, Fla. | W 1-0 |
| Thu Oct 21, 7:00 ET | vs Syracuse Clemson, SC | W 8-0 |
| Sun Oct 24, 1:00 ET | vs Louisville Clemson, SC | T 1-1 |
| Thu Oct 28, 5:00 ET | at Boston College Newton, Mass. | W 4-1 |
| Sun Oct 31, 6:00 ET | at Notre Dame South Bend, Ind. / ACC Championship First Round | W 3-2 |
| Fri Nov 5, 5:30 ET | vs Virginia Cary, N.C. / ACC Championship Semifinals | L 0-1 |
| Fri Nov 12, 4:00 ET | vs Alabama Clemson, SC (NCAA Tournament) | L 0-1 |