| Date | Game | |
| Sat Jan 14, 12:00 ET | vs College of Charleston Clemson, SC | W 7-0 |
| Sat Jan 14, 5:00 ET | vs UNC Greensboro Clemson, SC | W 7-0 |
| Sun Jan 22, 11:00 AM ET | vs Presbyterian Clemson, SC | W 7-0 |
| Sun Jan 22, 3:00 ET | vs Wofford Clemson, SC | W 7-0 |
| Sat Jan 28 | at Pepperdine Malibu, CA | L 0-4 |
| Sun Jan 29 | vs Columbia Malibu, CA | W 4-0 |
| Fri Feb 3, 1:00 ET | vs Georgia Southern | W 7-0 |
| Sat Feb 11, 11:00 AM ET | vs Elon Clemson, SC | W 6-1 |
| Sat Feb 11, 3:00 ET | vs App State Clemson, SC | W 4-0 |
| Tue Feb 14, 3:00 ET | vs South Carolina Clemson, SC | W 4-2 |
| Sun Feb 19, 4:00 ET | vs Coastal Carolina Clemson, SC | W 7-0 |
| Fri Feb 24, 4:00 ET | at Louisville Louisville, KY | W 4-3 |
| Sun Feb 26, 11:00 AM ET | at Notre Dame South Bend, IN | L 1-4 |
| Fri Mar 3, 5:00 ET | at Wake Forest Winston-Salem, NC | L 2-5 |
| Sun Mar 5, 12:00 ET | at NC State Raleigh, NC | L 1-6 |
| Fri Mar 10, 3:00 ET | vs Duke Clemson, SC | L 2-5 |
| Sun Mar 12, 12:00 ET | vs North Carolina Clemson, SC | L 1-6 |
| Fri Mar 17, 3:00 ET | vs Syracuse Clemson, SC | W 6-1 |
| Sun Mar 19, 11:00 AM ET | vs Boston College Clemson, SC | L 1-4 |
| Fri Mar 31, 2:00 ET | at Virginia Tech Blacksburg, VA | W 4-3 |
| Sun Apr 2, 12:00 ET | at Virginia Charlottesville, VA | L 3-4 |
| Sat Apr 8, 12:00 ET | vs Georgia Tech Clemson, SC | L 2-5 |
| Fri Apr 14, 3:00 ET | vs Miami Clemson, SC | L 0-7 |
| Sun Apr 16, 11:30 AM ET | vs Florida State Clemson, SC | L 1-4 |
| Wed Apr 19 | vs Virginia Tech Cary, NC | W 4-3 |
| Thu Apr 20, 10:00 AM ET | vs Miami Cary, NC | L 0-4 |