| Date | Game | |
| Sat Aug 28, 11:00 AM ET | vs Samford Clemson, S.C. | W 3-0 |
| Sat Aug 28, 7:00 ET | vs North Carolina A&T Clemson, S.C. | W 3-1 |
| Thu Sep 2, 12:00 ET | vs UCF Columbia, S.C. | L 1-3 |
| Fri Sep 3, 1:00 ET | at South Carolina Columbia, SC | L 0-3 |
| Sun Sep 5, 4:00 ET | vs Gardner-Webb Clemson, S.C. | W 3-0 |
| Fri Sep 10, 7:00 ET | at Kennesaw State Kennesaw, Ga. | W 3-1 |
| Sat Sep 11, 1:00 ET | at Santa Clara Kennesaw, Ga. | L 1-3 |
| Wed Sep 15, 7:00 ET | vs Georgia State Clemson, S.C. | W 3-0 |
| Fri Sep 17, 12:00 ET | vs UNC Asheville Clemson, S.C. | W 3-0 |
| Fri Sep 17, 6:30 ET | vs Rutgers Clemson, S.C. | W 3-0 |
| Sat Sep 18, 11:00 AM ET | vs ETSU Clemson, S.C. | W 3-1 |
| Fri Sep 24, 6:00 ET | at Virginia Tech Blacksburg, Va. | W 3-0 |
| Sun Sep 26, 1:00 ET | at Wake Forest Winston-Salem, N.C. | W 3-2 |
| Fri Oct 1, 7:00 ET | vs Louisville Clemson, SC | L 0-3 |
| Sun Oct 3, 1:00 ET | vs Notre Dame Clemson, S.C. | L 0-3 |
| Fri Oct 8, 5:00 ET | at Pitt Pittsburgh, Pa. | L 0-3 |
| Sun Oct 10, 1:00 ET | at Virginia Charlottesville, Va. | W 3-2 |
| Wed Oct 13, 8:00 ET | vs Georgia Tech Clemson, S.C. | L 0-3 |
| Fri Oct 15, 7:00 ET | vs Duke Clemson, S.C. | L 0-3 |
| Fri Oct 22, 8:00 ET | at Boston College Chestnut Hill, MA | L 1-3 |
| Sun Oct 24, 1:00 ET | at Syracuse Syracuse, NY | L 0-3 |
| Fri Oct 29, 7:00 ET | vs NC State Clemson, S.C. | L 1-3 |
| Sun Oct 31, 1:00 ET | vs North Carolina Clemson, S.C. | L 2-3 |
| Fri Nov 5, 7:00 ET | vs Florida State Clemson, S.C. | L 1-3 |
| Sun Nov 7 | vs Miami Clemson, SC | L 0-3 |
| Wed Nov 10, 5:00 ET | vs Southern Miss Clemson, S.C. | W 3-1 |
| Sat Nov 13, 5:00 ET | at Miami Coral Gables, Fla. | L 1-3 |
| Sun Nov 21, 1:00 ET | vs Pitt Clemson, S.C. | L 0-3 |
| Wed Nov 24, 2:00 ET | at Georgia Tech Atlanta, Ga. | L 0-3 |
| Sat Nov 27, 1:00 ET | at NC State Raleigh, N.C. | L 1-3 |