| Date | Game | |
| Sat Feb 20, 2:00 ET | at Coastal Carolina Conway, S.C. | W 12-4 |
| Sun Feb 21, 12:00 ET | at Coastal Carolina Conway, S.C. | L 7-8 |
| Sun Feb 21, 3:00 ET | at Coastal Carolina Conway, SC. | W 10-9 |
| Tue Feb 23, 4:00 ET | at East Carolina Greenville, N.C. | L 1-6 |
| Fri Feb 26, 3:00 ET | vs Boston College | L 6-10 |
| Sat Feb 27, 3:00 ET | vs Boston College Durham, N.C. | W 10-3 |
| Sun Feb 28, 1:00 ET | vs Boston College Durham, N.C. | L 2-5 |
| Tue Mar 2, 4:00 ET | vs Davidson Durham, N.C. | W 7-3 |
| Fri Mar 5, 4:00 ET | vs Pittsburgh Durham, N.C. | W 3-1 |
| Sat Mar 6, 3:00 ET | vs Pittsburgh Durham, N.C. | W 8-1 |
| Sun Mar 7, 1:00 ET | vs Pittsburgh Durham, N.C. | L 4-5 |
| Tue Mar 9, 4:00 ET | vs East Carolina Durham, N.C. | L 5-11 |
| Tue Mar 16, 4:00 ET | vs NC Central Durham, N.C. | W 7-4 |
| Fri Mar 19, 4:00 ET | at Notre Dame South Bend, Ind. | L 4-6 |
| Sat Mar 20, 2:00 ET | at Notre Dame South Bend, Ind. | L 2-6 |
| Sun Mar 21, 1:00 ET | at Notre Dame South Bend, Ind. | W 2-0 |
| Tue Mar 23, 4:00 ET | vs UNC Greensboro Durham, NC | W 5-2 |
| Fri Mar 26, 7:00 ET | vs Georgia Tech Durham, N.C. | L 2-5 |
| Sat Mar 27, 7:00 ET | vs Georgia Tech Durham, N.C. | L 0-3 |
| Sun Mar 28, 11:00 AM ET | vs Georgia Tech Durham, N.C. | W 9-7 |
| Tue Mar 30, 4:00 ET | vs Liberty Durham, N.C. | W 5-4 |
| Fri Apr 2, 7:00 ET | at Miami Coral Gables, Fla. | L 1-3 |
| Sat Apr 3, 7:00 ET | at Miami Coral Gables, Fla. | L 5-11 |
| Sun Apr 4, 1:00 ET | at Miami Coral Gables, Fla. | L 1-7 |
| Tue Apr 6, 6:00 ET | vs NC Central Durham, N.C. | W 12-7 |
| Fri Apr 9, 6:00 ET | at North Carolina Chapel Hill, N.C. | W 4-2 |
| Sun Apr 11, 12:00 ET | at North Carolina Chapel Hill, N.C. | L 5-11 |
| Sun Apr 11, 12:00 ET | at North Carolina Chapel Hill, N.C. | L 5-11 |
| Sun Apr 11, 12:00 ET | at North Carolina Chapel Hill, NC | L 5-11 |
| Mon Apr 12, 6:00 ET | at North Carolina Chapel Hill, N.C. | L 8-21 |
| Tue Apr 13, 6:00 ET | vs Campbell Durham, N.C. | W 14-7 |
| Fri Apr 16, 6:00 ET | vs Wake Forest Durham, N.C. | L 0-11 |
| Fri Apr 16, 6:00 ET | vs Wake Forest Durham, NC | L 0-11 |
| Sat Apr 17, 3:00 ET | vs Wake Forest Durham, NC | W 11-2 |
| Sat Apr 17, 3:00 ET | vs Wake Forest Durham, N.C. | W 11-2 |
| Sat Apr 17, 3:00 ET | vs Wake Forest Durham, N.C. | |
| Sat Apr 17, 3:00 ET | vs Wake Forest Durham, N.C. | W 11-2 |
| Tue Apr 20, 6:00 ET | at Liberty Lynchburg, Va. | W 7-0 |
| Fri Apr 23, 4:00 ET | at Virginia Charlottesville, Va. | L 3-9 |
| Sat Apr 24, 10:00 AM ET | at Virginia Charlottesville, Va. | L 3-4 |
| Sun Apr 25, 2:00 ET | at Virginia Charlottesville, Va. | W 7-4 |
| Tue May 4, 6:00 ET | vs William & Mary Durham, N.C. | W 11-6 |
| Fri May 7, 6:00 ET | at Louisville Louisville, Ky. | W 13-3 |
| Sat May 8, 1:00 ET | at Louisville Louisville, Ky. | L 1-5 |
| Sat May 8, 4:30 ET | at Louisville Louisville, Ky. | L 6-15 |
| Tue May 11, 6:00 ET | vs Wofford Durham, N.C. | W 9-6 |
| Fri May 14, 6:00 ET | vs Virginia Tech Durham, N.C. | W 11-6 |
| Sat May 15, 1:00 ET | vs Virginia Tech Durham, N.C. | W 4-1 |
| Sun May 16, 1:00 ET | vs Virginia Tech Durham, N.C. | W 2-1 |
| Tue May 18, 4:00 ET | at Davidson Davidson, N.C. | W 18-2 |
| Thu May 20, 6:00 ET | at Clemson Clemson, S.C. | W 5-1 |
| Fri May 21, 6:00 ET | at Clemson Clemson, S.C. | W 14-8 |
| Sat May 22, 1:00 ET | at Clemson Clemson, S.C. | W 4-2 |
| Wed May 26, 11:00 AM ET | vs Florida State Charlotte, NC | W 12-1 |
| Thu May 27, 11:00 AM ET | vs Miami Charlotte, NC | W 3-2 |
| Sat May 29, 1:00 ET | vs Virginia Charlotte, NC | W 4-2 |
| Sun May 30, 12:00 ET | vs NC State Charlotte, NC | W 1-0 |
| Fri Jun 4, 12:00 ET | vs Liberty Knoxville, Tenn. / NCAA Regional | L 6-11 |
| Sat Jun 5, 12:00 ET | vs Wright State Knoxville, Tenn. / NCAA Regional | W 14-6 |
| Sun Jun 6, 2:00 ET | vs Liberty Knoxville, Tenn. / NCAA Regional | L 4-15 |