| Date | Game | |
| Thu Feb 9, 10:00 AM ET | vs Washington Irvine, CA | L 3-4 |
| Thu Feb 9, 4:00 ET | vs Oklahoma Irvine, CA | L 0-4 |
| Fri Feb 10, 9:00 AM ET | vs San Jose State Irvine, CA | W 11-2 |
| Fri Feb 10, 2:00 ET | vs Liberty Irvine, CA | W 8-5 |
| Sat Feb 11, 3:30 ET | vs Stanford Irvine, CA | W 4-2 |
| Thu Feb 16, 1:00 ET | vs Alabama Clearwater, FL | L 4-5 |
| Fri Feb 17, 1:00 ET | vs UCF Clearwater, FL | W 5-2 |
| Fri Feb 17, 6:00 ET | vs Arkansas Clearwater, FL | W 7-4 |
| Sat Feb 18, 10:00 AM ET | vs UCF Clearwater, FL | W 4-3 |
| Sun Feb 19, 9:00 AM ET | vs Michigan Clearwater, FL | W 6-3 |
| Wed Feb 22, 3:00 ET | vs Charleston Southern Durham, N.C. | W 9-1 |
| Wed Feb 22, 5:00 ET | vs Charleston Southern Durham, N.C. | W 8-0 |
| Fri Feb 24, 11:30 AM ET | vs Rider Buies Creek, N.C. | W 4-0 |
| Fri Feb 24, 4:30 ET | vs Campbell Buies Creek, N.C. | W 7-0 |
| Sun Feb 26, 12:00 ET | vs Ohio Buies Creek, N.C. | W 7-0 |
| Sun Feb 26, 2:00 ET | vs Campbell Buies Creek, N.C. | W 11-0 |
| Wed Mar 1, 4:00 ET | vs NC Central Durham, N.C. | W 12-0 |
| Wed Mar 1, 6:00 ET | vs NC Central Durham, N.C. | W 8-0 |
| Fri Mar 3, 4:00 ET | vs Notre Dame Durham, N.C. | L 4-5 |
| Sat Mar 4, 2:00 ET | vs Notre Dame Durham, N.C. | W 6-2 |
| Sun Mar 5, 12:00 ET | vs Notre Dame Durham, N.C. | W 4-3 |
| Wed Mar 8, 5:00 ET | at Charlotte Charlotte, N.C. | W 5-4 |
| Fri Mar 10, 6:00 ET | vs Louisville Durham, N.C. | W 9-6 |
| Sat Mar 11, 2:00 ET | vs Louisville Durham, N.C. | W 5-3 |
| Sat Mar 11, 4:30 ET | vs Louisville Durham, N.C. | L 9-13 |
| Wed Mar 15, 6:00 ET | vs James Madison Durham, N.C. | W 5-0 |
| Fri Mar 17, 1:00 ET | at North Carolina Chapel Hill, N.C. | W 9-7 |
| Sat Mar 18, 2:00 ET | at North Carolina Chapel Hill, N.C. | W 7-5 |
| Sun Mar 19, 1:00 ET | at North Carolina Chapel Hill, N.C. | W 8-0 |
| Tue Mar 21, 6:00 ET | vs Liberty Durham, N.C. | W 7-2 |
| Fri Mar 24 | vs Florida State Durham, N.C. | L 1-4 |
| Fri Mar 24, 6:00 ET | vs Florida State Durham, N.C. | L 1-4 |
| Sat Mar 25, 1:00 ET | vs Florida State Durham, N.C. | W 2-1 |
| Sun Mar 26, 12:00 ET | vs Florida State Durham, N.C. | L 3-7 |
| Sat Apr 1, 12:00 ET | at Virginia Tech Blacksburg, VA | W 7-1 |
| Sun Apr 2, 12:00 ET | at Virginia Tech Blacksburg, VA | W 5-1 |
| Sun Apr 2, 2:00 ET | at Virginia Tech Blacksburg, VA | L 8-13 |
| Wed Apr 5, 2:00 ET | at UNCW Wilmington, NC | W 8-0 |
| Wed Apr 5, 4:30 ET | at UNCW Wilmington, NC | W 5-3 |
| Mon Apr 10, 3:30 ET | vs Elon Elon, NC | W 4-0 |
| Wed Apr 12, 4:00 ET | vs East Carolina Durham, N.C. | W 11-5 |
| Wed Apr 12, 7:00 ET | vs East Carolina Durham, N.C. | W 4-3 |
| Fri Apr 14, 4:00 ET | at Boston College Chestnut Hill, MA | W 6-4 |
| Sat Apr 15, 1:00 ET | at Boston College Chestnut Hill, MA | W 3-0 |
| Sun Apr 16, 12:00 ET | at Boston College Chestnut Hill, MA | W 4-2 |
| Wed Apr 19, 6:00 ET | vs UNC Greensboro Durham, N.C. | W 8-1 |
| Fri Apr 21, 4:00 ET | vs Georgia Tech Durham, N.C. | W 11-3 |
| Fri Apr 21, 7:00 ET | vs Georgia Tech Durham, N.C. | W 4-3 |
| Sun Apr 23, 12:00 ET | vs Georgia Tech Durham, N.C. | W 6-2 |
| Wed Apr 26, 5:00 ET | at Longwood University Farmville, VA | L 3-4 |
| Fri Apr 28, 4:00 ET | at Pitt Pittsburgh, PA | W 4-3 |
| Sat Apr 29, 1:00 ET | at Pitt Pittsburgh, PA | W 12-3 |
| Sat Apr 29, 3:30 ET | at Pitt Pittsburgh, PA | W 12-4 |
| Thu May 11, 5:00 ET | vs Georgia Tech South Bend, IN / ACC Championship | W 7-1 |
| Fri May 12, 1:30 ET | vs Clemson South Bend, Ind. / ACC Championship | W 2-0 |
| Fri May 19, 12:00 ET | vs George Mason Durham, NC / NCAA Regional | W 2-1 |
| Sat May 20, 1:00 ET | vs Charlotte Durham, NC / NCAA Regional | W 5-0 |
| Sun May 21, 12:00 ET | vs Charlotte Durham, NC / NCAA Regional | W 4-2 |
| Fri May 26, 12:00 ET | vs Stanford Durham, NC / NCAA Super Regional | L 1-3 |
| Sat May 27, 3:00 ET | vs Stanford Durham, NC / NCAA Super Regional | L 2-7 |