| Date | Game | |
| Mon Nov 3, 12:00 ET | vs Baylor | ESPN |
| Sun Nov 9, 1:00 ET | vs Holy Cross Durham, N.C. | ACCNX |
| Wed Nov 12, 7:00 ET | vs Norfolk State Durham, N.C. | ACCNX |
| Fri Nov 14, 7:00 ET | vs West Virginia White Sulphur Springs, W. Va. | ESPNU |
| Sun Nov 16, 2:00 ET | at Liberty Lynchburg, Va. | |
| Thu Nov 20 | at South Florida Tampa, Fla. | |
| Wed Nov 26, 4:30 ET | vs South Carolina Las Vegas, Nev. | truTV |
| Thu Nov 27 | vs TBD Las Vegas, Nev. | truTV |
| Thu Dec 4, 9:00 ET | vs LSU Durham, N.C. | ESPN |
| Sun Dec 7, 2:00 ET | at Virginia Tech Blacksburg, Va. | ACCN |
| Thu Dec 18, 7:00 ET | vs South Dakota State Durham, N.C. | ACCN |
| Sat Dec 20, 2:00 ET | at Belmont Nashville, Tenn. | |
| Sun Dec 28, 4:00 ET | at Syracuse Syracuse, N.Y. | ACCN |
| Thu Jan 1, 1:00 ET | vs Boston College Durham, N.C. | ACCNX |
| Sun Jan 4 | vs Notre Dame Durham, N.C. | ESPN/ACCN |
| Thu Jan 8, 6:00 ET | at California Berkeley, Calif. | ACCN |
| Sun Jan 11, 5:00 ET | at Stanford Stanford, CA | ESPN |
| Thu Jan 15, 8:00 ET | vs Virginia Durham, N.C. | ACCN |
| Sun Jan 18, 6:00 ET | vs Georgia Tech Durham, N.C. | ACCN |
| Sun Jan 25, 2:00 ET | at Pitt Pittsburgh, Pa. | ACCN |
| Thu Jan 29, 8:00 ET | at Miami Coral Gables, FL | ACCN |
| Sun Feb 1, 12:00 ET | vs Wake Forest Durham, N.C. | ACCN |
| Thu Feb 5, 7:00 ET | at Louisville Louisville, KY | ESPN |
| Sun Feb 8, 2:00 ET | vs SMU Durham, N.C. | The CW |
| Sun Feb 15, 1:00 ET | vs North Carolina Durham, N.C. | ABC |
| Thu Feb 19, 7:00 ET | vs NC State Durham, N.C. | ESPN |
| Sun Feb 22, 2:00 ET | at Clemson Clemson, SC | ESPN/ESPN2 |
| Thu Feb 26, 8:00 ET | vs Florida State Durham, NC | ACCN |
| Sun Mar 1, 12:00 ET | at North Carolina Chapel Hill, N.C. | ESPN |