| Date | Game | |
| Fri Aug 25, 7:00 ET | vs Northeastern LOUISVILLE, KY | W 3-1 |
| Sun Aug 27, 3:00 ET | at Northwestern Evanston, IL | W 1-0 |
| Fri Sep 1, 11:00 AM ET | vs Princeton Philadelphia, PA | W 2-1 |
| Sun Sep 3, 1:30 ET | at Penn Philadelphia, PA | W 2-1 |
| Fri Sep 8, 6:00 ET | vs Ohio State LOUISVILLE, KY | W 2-1 |
| Sun Sep 10, 12:00 ET | vs VCU LOUISVILLE, KY | W 2-1 |
| Fri Sep 15, 3:00 ET | at North Carolina Chapel Hill | L 0-2 |
| Fri Sep 22, 5:00 ET | vs JMU LOUISVILLE, KY | W 4-1 |
| Tue Sep 26, 2:00 ET | at Miami University Oxford, OH | W 2-0 |
| Fri Sep 29, 3:00 ET | vs Virginia LOUISVILLE, KY | W 2-0 |
| Fri Oct 6, 6:00 ET | vs Wake Forest LOUISVILLE, KY | W 1-0 |
| Sun Oct 8, 12:00 ET | vs Central Michigan LOUISVILLE, KY | W 3-0 |
| Tue Oct 10, 12:00 ET | at Indiana Bloomington, IN | W 1-0 |
| Fri Oct 13, 4:00 ET | at Duke Durham, NC | L 1-2 |
| Sun Oct 15, 12:00 ET | vs Iowa LOUISVILLE, KY | L 1-2 |
| Fri Oct 20, 6:00 ET | vs Syracuse LOUISVILLE, KY | L 1-4 |
| Sun Oct 22, 12:00 ET | vs Appalachian State LOUISVILLE, KY | L 1-2 |
| Fri Oct 27, 2:00 ET | at Boston College Chestnut Hill, MA | W 2-1 |
| Tue Oct 31, 6:00 ET | vs Boston College Charlottesville, VA / ACC Championship | W 3-2 |
| Wed Nov 1, 3:30 ET | vs Duke Charlottesville, VA / ACC Championship | L 0-1 |
| Fri Nov 10, 3:30 ET | vs Iowa Evanston, Ill. | W 2-1 |
| Sun Nov 12, 2:00 ET | at Northwestern Evanston, Ill. | L 2-3 |