| Date | Game | |
| Thu Aug 25, 5:00 ET | vs Saint Louis Louisville, Ky. | W 3-1 |
| Mon Aug 29, 7:30 ET | vs Bellarmine Louisville, Ky. | W 3-0 |
| Fri Sep 2, 7:30 ET | vs Seattle Louisville, Ky. | W 2-1 |
| Tue Sep 6, 7:30 ET | at Kentucky Lexington, Ky. | L 2-3 |
| Sat Sep 10, 7:30 ET | vs Duke Louisville, Ky. | L 1-2 |
| Fri Sep 16, 7:00 ET | at Boston College Newton, MA | T 1-1 |
| Mon Sep 19, 7:00 ET | at Florida Gulf Coast Fort Myers, Fla. | W 1-0 |
| Fri Sep 23, 8:00 ET | vs Pitt Louisville, KY | W 2-1 |
| Tue Sep 27, 7:30 ET | vs UNC Greensboro Louisville, Ky. | T 1-1 |
| Fri Sep 30, 12:00 ET | at NC State Raleigh, N.C. | W 1-0 |
| Sat Oct 8, 7:00 ET | at Notre Dame South Bend, Ind. | W 2-0 |
| Tue Oct 11, 7:00 ET | vs Evansville Louisville, Ky. | W 2-0 |
| Fri Oct 14, 7:00 ET | vs Syracuse Louisville, KY | L 1-2 |
| Tue Oct 18, 7:00 ET | vs East Tennessee State Louisville, Ky. | T 1-1 |
| Fri Oct 21, 7:00 ET | vs Clemson Louisville, Ky. | W 1-0 |
| Fri Oct 28, 8:00 ET | at Wake Forest Winston-Salem, N.C. | L 0-3 |
| Wed Nov 2, 6:00 ET | vs Virginia Tech Louisville, KY | L 1-2 |
| Thu Nov 17, 7:00 ET | vs Western Michigan Louisville, KY | L 1-2 |