| Date | Game | |
| Thu Aug 22, 5:00 ET | vs Jacksonville Louisville, Ky. | W 2-0 |
| Wed Aug 28, 8:00 ET | at Tulsa Tulsa, OK | W 2-1 |
| Mon Sep 2, 7:00 ET | vs Bellarmine Louisville, Ky. | W 3-1 |
| Fri Sep 6, 7:00 ET | vs Notre Dame Louisville, Ky. | L 1-2 |
| Mon Sep 9, 7:30 ET | at Kentucky Lexington, Ky. | W 1-0 |
| Fri Sep 13, 7:00 ET | at Pitt Pittsburgh, PA | L 2-3 |
| Fri Sep 20, 7:00 ET | vs Syracuse Louisville, KY | T 1-1 |
| Tue Sep 24, 7:00 ET | vs UAB Louisville, Ky. | L 1-2 |
| Sun Sep 29, 3:00 ET | at Boston College Newton, Mass. | T 1-1 |
| Thu Oct 3, 6:00 ET | at Cal Berkeley, Calif. | T 3-3 |
| Tue Oct 8, 7:00 ET | vs Lipscomb Louisville, Ky. | W 4-2 |
| Fri Oct 11, 8:00 ET | vs Clemson Louisville, Ky. | L 2-3 |
| Wed Oct 16, 7:00 ET | vs Evansville Louisville, Ky. | T 2-2 |
| Tue Oct 22, 7:00 ET | vs Milwaukee Louisville, Ky. | W 4-0 |
| Sun Oct 27, 6:00 ET | at NC State Raleigh, NC | L 0-1 |
| Fri Nov 1, 7:00 ET | vs SMU Louisville, KY | L 2-3 |
| Wed Nov 6, 6:00 ET | at Clemson Clemson, SC | L 1-3 |