| Date | Game | |
| Thu Aug 19, 7:30 ET | vs Western Michigan Louisville, KY | W 6-2 |
| Fri Aug 27, 7:30 ET | vs James Madison Louisville, KY | W 4-3 |
| Sun Aug 29, 7:30 ET | vs Northern Kentucky Louisville, KY | W 3-0 |
| Thu Sep 2, 8:00 ET | at Saint Louis Saint Louis, MO | W 1-0 |
| Sun Sep 5, 7:30 ET | vs Western Kentucky Louisville, KY | L 0-1 |
| Fri Sep 17, 7:00 ET | at Miami Coral Gables, FL | W 3-2 |
| Thu Sep 23, 6:00 ET | at Syracuse Syracuse, N.Y. | W 2-1 |
| Sun Sep 26, 1:00 ET | vs FLORIDA STATE Louisville, KY | L 0-3 |
| Sat Oct 2, 7:00 ET | vs WAKE FOREST Louisville, KY | W 2-1 |
| Thu Oct 7, 8:00 ET | at Notre Dame South Bend, Ind. | L 0-3 |
| Sun Oct 10, 1:00 ET | vs NC STATE Louisville, KY | L 1-2 |
| Fri Oct 15, 4:00 ET | vs BOSTON COLLEGE Louisville, KY | L 1-2 |
| Thu Oct 21, 7:00 ET | at Virginia Charlottesville, VA | L 1-4 |
| Sun Oct 24, 1:00 ET | at Clemson Clemson, SC | T 1-1 |
| Thu Oct 28, 5:00 ET | vs DUKE Louisville, KY | L 0-1 |