| Date | Game | |
| Fri Sep 19 | at Cincinnati Invitational Cincinnati OH | |
| Fri Oct 3 | at Indiana Invitational Bloomington, IN | |
| Thu Oct 16 | at Ohio Valley Regional Knoxville, TN | |
| Fri Nov 7 | at North Florida Fall Invitational Jacksonville, FL | |
| Sat Jan 17, 3:00 ET | vs Dayton Louisville, KY | |
| Mon Jan 19, 3:00 ET | vs Western Kentucky Louisville, KY | |
| Fri Jan 30, 3:00 ET | vs Northern Kentucky Louisville, KY | W 7-0 |
| Sun Feb 1, 11:00 AM ET | vs Eastern Kentucky Louisville, KY | W 7-0 |
| Sun Feb 8, 12:00 ET | vs Southern Indiana Louisville, KY | W 4-0 |
| Fri Feb 13, 4:00 ET | vs Notre Dame Louisville, KY | L 1-4 |
| Sun Feb 15, 12:00 ET | vs Indiana Louisville, KY | W 4-1 |
| Fri Feb 20, 4:00 ET | vs Florida State Louisville, KY | W 4-3 |
| Sun Feb 22, 12:00 ET | vs Miami Louisville, KY | L 0-4 |
| Fri Feb 27, 4:00 ET | at Georgia Tech Atlanta, GA | L 0-4 |
| Fri Feb 27, 4:00 ET | at Georgia Tech Atlanta, GA | |
| Sun Mar 1, 12:00 ET | at Clemson Clemson, SC | L 0-4 |
| Sat Mar 7, 3:00 ET | at Xavier Cincinnati, OH | W 4-2 |
| Wed Mar 11, 3:00 ET | vs Middle Tennessee Louisville, KY | W 6-1 |
| Fri Mar 13, 5:00 ET | at Duke Durham, NC | L 0-4 |
| Sun Mar 15, 1:00 ET | at North Carolina Chapel Hill, NC | L 0-4 |
| Fri Mar 20, 2:00 ET | vs SMU Louisville, KY | L 0-4 |
| Fri Mar 27, 4:00 ET | vs California Louisville, KY | L 1-4 |
| Sun Mar 29, 12:00 ET | vs Stanford Louisville, KY | L 1-4 |
| Fri Apr 3, 3:00 ET | at NC State Raleigh, NC | L 0-7 |
| Sun Apr 5, 12:00 ET | at Wake Forest Winston-Salem, NC | L 0-4 |
| Sat Apr 11, 2:00 ET | vs Austin Peay Louisville, KY | W 4-0 |
| Tue Apr 14 | vs ACC Championship Cary, NC | |
| Tue Apr 14 | vs Virginia Tech Cary, NC (ACC Championship) | L 2-4 |