| Date | Game | |
| Fri Feb 18, 7:00 ET | vs Manhattan Deland, FL | W 17-2 |
| Sat Feb 19, 4:00 ET | at Stetson DeLand, FL | W 5-3 |
| Sun Feb 20, 9:00 AM ET | vs Delaware Deland, FL | L 4-5 |
| Fri Feb 25, 4:00 ET | vs Marist Greenville, SC | W 20-2 |
| Sat Feb 26, 2:00 ET | vs Monmouth Greenville, SC | W 16-2 |
| Sat Feb 26, 6:00 ET | vs Monmouth Greenville, SC | W 9-0 |
| Fri Mar 4, 4:00 ET | vs Illinois Minneapolis, MN | W 6-1 |
| Sat Mar 5, 12:00 ET | vs Michigan State Minneapolis, MN | W 2-1 |
| Sun Mar 6, 7:00 ET | at University of Minnesota Minneapolis, MN | W 3-1 |
| Tue Mar 8, 4:00 ET | at Elon University Elon, NC | W 11-3 |
| Fri Mar 11, 4:00 ET | at NC State | W 8-4 |
| Sun Mar 13, 1:00 ET | at NC State | W 11-4 |
| Tue Mar 15, 5:00 ET | vs Valparaiso | W 12-1 |
| Fri Mar 18, 4:00 ET | at Louisville | L 11-16 |
| Sat Mar 19, 1:00 ET | at Louisville | L 1-8 |
| Sun Mar 20, 1:00 ET | at Louisville | L 5-7 |
| Fri Mar 25, 4:00 ET | vs Virginia Tech | L 5-10 |
| Tue Mar 29, 5:00 ET | vs Northern Illinois | W 11-2 |
| Fri Apr 1, 8:00 ET | at Florida State | W 2-0 |
| Sat Apr 2, 2:00 ET | at Florida State | W 5-4 |
| Sun Apr 3, 1:00 ET | at Florida State | W 9-7 |
| Tue Apr 5, 5:00 ET | vs Butler | W 5-2 |
| Fri Apr 8, 4:00 ET | vs Clemson | W 4-1 |
| Sat Apr 9, 2:00 ET | vs Clemson | W 8-1 |
| Sun Apr 10, 1:00 ET | vs Clemson | W 9-3 |
| Tue Apr 12, 6:30 ET | vs Michigan | W 14-5 |
| Thu Apr 14, 4:00 ET | at Duke Durham, NC | L 5-15 |
| Fri Apr 15, 6:00 ET | at Duke Durham, N.C. | L 3-4 |
| Sat Apr 16, 12:00 ET | at Duke | L 2-6 |
| Tue Apr 19, 5:00 ET | vs Valparisio | W 5-1 |
| Wed Apr 20, 5:00 ET | vs Purdue Fort Wayne | W 12-2 |
| Fri Apr 22, 5:00 ET | vs Wake Forest South Bend, Ind. | W 8-3 |
| Sat Apr 23, 2:00 ET | vs Wake Forest | W 21-3 |
| Sun Apr 24, 11:00 AM ET | vs Wake Forest | W 13-12 |
| Tue Apr 26, 6:30 ET | vs Michigan State University Detroit, MI | L 2-6 |
| Fri Apr 29, 5:00 ET | vs Boston College Notre Dame, Ind. | L 4-7 |
| Sat Apr 30, 1:00 ET | vs Boston College Notre Dame, Ind. | W 11-5 |
| Sun May 1, 1:00 ET | vs Boston College Notre Dame, Ind. | W 16-10 |
| Tue May 10, 6:00 ET | vs Michigan State | W 15-6 |
| Fri May 13, 6:00 ET | vs Pitt South Bend, Ind. | W 8-3 |
| Sat May 14, 5:00 ET | vs Pitt South Bend, Ind. | W 8-1 |
| Sun May 15, 12:00 ET | vs Pitt South Bend, Ind. | L 2-5 |
| Tue May 17, 4:00 ET | at Northwestern University Evanston, IL | W 14-4 |
| Thu May 19, 7:00 ET | at Miami | L 4-6 |
| Fri May 20, 7:00 ET | at Miami | W 5-0 |
| Sat May 21, 1:00 ET | at Miami | L 7-16 |
| Thu May 26, 3:00 ET | vs Florida State Charlotte, N.C. / ACC Championship | W 5-3 |
| Fri May 27, 11:00 AM ET | vs Virginia Charlotte, N.C. / ACC Championship | W 3-0 |
| Sat May 28, 1:00 ET | vs North Carolina Charlotte, N.C. / ACC Championship | L 2-7 |
| Fri Jun 3, 2:00 ET | vs Texas Tech Statesboro, Ga. / NCAA Regional | W 3-2 |
| Sat Jun 4, 8:00 ET | at Georgia Southern Statesboro, Ga. / NCAA Regional | W 6-4 |
| Sun Jun 5, 7:00 ET | vs Texas Tech Statesboro, Ga. / NCAA Regional | W 4-3 |
| Fri Jun 10, 6:00 ET | at Tennessee Knoxville, Tenn. / NCAA Super Regional | W 8-6 |
| Sat Jun 11, 2:00 ET | at Tennessee Knoxville, Tenn. / NCAA Super Regional | L 4-12 |
| Sun Jun 12, 1:00 ET | at Tennessee Knoxville, Tenn. / NCAA Super Regional | W 7-3 |
| Fri Jun 17, 7:00 ET | vs Texas Omaha, Neb. / College World Series | W 7-3 |
| Sun Jun 19, 7:00 ET | vs Oklahoma Omaha, Neb. / College World Series | L 2-6 |
| Tue Jun 21, 2:00 ET | vs Texas A&M Omaha, Neb. / College World Series | L 1-5 |