| Date | Game | |
| Mon Nov 3, 7:00 ET | vs Long Island South Bend, Ind. | W 89-67 |
| Fri Nov 7, 7:00 ET | vs Detroit Mercy South Bend, Ind. | W 102-70 |
| Tue Nov 11, 7:30 ET | vs Eastern Illinois South Bend, Ind. | W 78-58 |
| Sun Nov 16, 12:30 ET | at Ohio State Columbus, OH | L 63-64 |
| Wed Nov 19, 7:00 ET | vs Bellarmine South Bend, Ind. | W 86-79 |
| Mon Nov 24, 3:30 ET | vs Kansas Las Vegas, NV | L 61-71 |
| Tue Nov 25, 1:00 ET | vs Rutgers Las Vegas, NV | W 68-63 |
| Wed Nov 26, 3:30 ET | vs Houston Las Vegas, NV | L 56-66 |
| Tue Dec 2, 9:00 ET | vs Missouri South Bend, Ind. | W 76-71 |
| Fri Dec 5, 8:00 ET | at TCU Fort Worth, TX | W 87-85 |
| Wed Dec 10, 7:00 ET | vs Idaho South Bend, Ind. | W 80-65 |
| Sat Dec 13, 2:00 ET | vs Evansville South Bend, Ind. | W 82-58 |
| Sun Dec 21, 2:00 ET | vs Purdue Fort Wayne South Bend, Ind. | L 69-72 |
| Tue Dec 30, 9:00 ET | at Stanford Palo Alto, CA | W 47-40 |
| Fri Jan 2, 11:00 ET | at California Berkeley, Calif. | L 71-72 |
| Sat Jan 10, 6:00 ET | vs Clemson South Bend, Ind. | L 61-76 |
| Tue Jan 13, 7:00 ET | vs Miami South Bend, Ind. | ESPNU |
| Sat Jan 17, 12:00 ET | at Virginia Tech Blacksburg, VA | ACCN |
| Wed Jan 21, 7:00 ET | at North Carolina Chapel Hill | ESPN2 |
| Sat Jan 24, 6:00 ET | vs Boston College South Bend, Ind. | ACCN |
| Tue Jan 27, 7:00 ET | vs Virginia South Bend, Ind. | |
| Sat Jan 31, 6:00 ET | at Syracuse Syracuse, NY | The CW |
| Wed Feb 4, 7:00 ET | at Louisville Louisville, KY | ESPN2/U |
| Sat Feb 7, 4:00 ET | vs Florida State South Bend, Ind. | ACCN |
| Tue Feb 10, 7:00 ET | at SMU Dallas, Texas | ACCN |
| Sat Feb 14, 12:00 ET | vs Georgia Tech South Bend, Ind. | The CW |
| Sat Feb 21, 2:00 ET | at Pitt Pittsburgh | ACCN |
| Tue Feb 24, 7:00 ET | vs Duke South Bend, Ind. | ESPN/ESPN2 |
| Sat Feb 28, 12:00 ET | vs NC State South Bend, IN | The CW |
| Wed Mar 4, 9:00 ET | vs Stanford South Bend, Ind. | ESPNU |
| Sat Mar 7, 12:00 ET | at Boston College Chestnut, Hill, Mass. | ESPNU |