| Date | Game | |
| Fri Jan 13, 11:00 AM ET | vs DePaul South Bend, IN | W 7-0 |
| Fri Jan 13, 11:00 AM ET | vs IUPUI South Bend, IN | W 6-1 |
| Sun Jan 15, 1:00 ET | at Northwestern Evanston, IL | L 0-4 |
| Sun Jan 15, 7:00 ET | at Chicago State Chicago, IL | W 5-0 |
| Fri Jan 20, 4:00 ET | vs Western Michigan South Bend, IN | W 4-3 |
| Fri Jan 27, 5:00 ET | at Washington Lexington, KY | W 4-2 |
| Sat Jan 28 | at Kentucky Lexington, KY | L 1-4 |
| Sat Feb 11, 7:00 ET | at Illinois Champaign, IL | L 0-7 |
| Sat Feb 18, 12:00 ET | vs Wisconsin South Bend, IN | W 5-2 |
| Sat Feb 18, 5:00 ET | vs UIC South Bend, IN | W 4-0 |
| Sat Feb 25, 1:00 ET | at Ohio State Columbus, OH | L 0-7 |
| Mon Feb 27 | vs Michigan State South Bend, Ind. | W 4-3 |
| Fri Mar 3, 4:00 ET | vs North Carolina South Bend, IN | L 2-4 |
| Sun Mar 5, 12:00 ET | vs Duke South Bend, IN | L 2-4 |
| Sun Mar 5, 5:00 ET | vs Northern Kentucky South Bend, IN | W 4-0 |
| Fri Mar 10, 4:00 ET | vs Virginia Tech South Bend, IN | W 4-3 |
| Sun Mar 12, 11:30 AM ET | vs Virginia South Bend, IN | L 2-5 |
| Fri Mar 17, 3:00 ET | at Miami Coral Gables, FL | L 3-4 |
| Sun Mar 19, 12:00 ET | at Florida State Tallahassee, FL | L 0-7 |
| Fri Mar 24, 5:30 ET | at NC State Raleigh, NC | L 0-4 |
| Sun Mar 26, 12:00 ET | at Wake Forest Winston-Salem, NC | L 1-6 |
| Sun Apr 2, 12:00 ET | vs Boston College South Bend, IN | W 6-1 |
| Sun Apr 2, 5:00 ET | vs Butler South Bend, IN | W 4-3 |
| Fri Apr 7, 5:00 ET | at Clemson Clemson, SC | W 4-3 |
| Sun Apr 9, 12:00 ET | at Georgia Tech Atlanta, GA | L 0-4 |
| Thu Apr 13, 3:00 ET | at Louisville Louisville, KY | L 0-4 |
| Thu Apr 20, 6:00 ET | vs Louisville Cary, NC | L 3-4 |