| Date | Game | |
| Sun Nov 1, 12:00 ET | vs Villanova Rome, Italy | FS1 |
| Fri Nov 6 | vs Stonehil South Bend, Ind. | |
| Tue Nov 10 | vs Detroit Mercy South Bend, Ind. | |
| Wed Nov 18 | vs Southern South Bend, Ind. | |
| Tue Nov 24, 1:00 ET | vs Davidson Paradise Island, Bahamas | ESPN+ |
| Thu Nov 26, 11:30 AM ET | vs West Virginia Paradise Island, Bahamas | ESPN2 |
| Thu Dec 3 | at Vanderbilt Nashville, TN | |
| Sun Dec 6 | vs Florida State South Bend, Ind. | |
| Wed Dec 9 | vs UConn South Bend, Ind. | |
| Sun Dec 13 | vs Bowling Green South Bend, Ind. | |
| Sat Dec 19, 11:00 ET | vs USC Las Vegas, Nev. | ESPN |
| Sun Dec 20, 7:30 ET | vs South Carolina Las Vegas, Nev. | ESPN |
| Mon Dec 28 | at Pitt Pittsburgh, Pa. | |
| Thu Dec 31 | vs California South Bend, Ind. | |
| Sun Jan 3 | at Miami Coral Gables, FL | |
| Thu Jan 7 | at Virginia Tech Blacksburg, Va. | |
| Sun Jan 10 | vs Duke South Bend, Ind. | |
| Thu Jan 14 | vs Georgia Tech South Bend, Ind. | |
| Sun Jan 17 | at Syracuse Syracuse, NY | |
| Thu Jan 21 | at Louisville Louisville, KY | |
| Thu Jan 28 | at North Carolina Chapel Hill, N.C. | |
| Sun Jan 31 | vs Stanford South Bend, Ind. | |
| Thu Feb 4 | vs SMU South Bend, Ind. | TBA |
| Sun Feb 7 | at Clemson Clemson, SC | |
| Thu Feb 11 | vs Virginia South Bend, Ind. | |
| Sun Feb 14 | vs Wake Forest South Bend, Ind. | |
| Thu Feb 18 | at NC State Raleigh, N.C. | |
| Sun Feb 21 | at Boston College Chestnut Hill, Mass. | |
| Sun Feb 28 | vs Louisville South Bend, Ind. | |