| Date | Game | |
| Fri Feb 11, 7:00 ET | vs Central Michigan South Bend, Ind. | W 24-5 |
| Sun Feb 13, 6:00 ET | vs Michigan South Bend, Ind. | L 7-11 |
| Sat Feb 19, 2:00 ET | at Vanderbilt Nashville, TN | L 12-14 |
| Wed Feb 23, 7:00 ET | vs Northwestern Nashville, TN | L 16-17 |
| Sat Feb 26, 6:00 ET | vs Syracuse South Bend, Ind. | L 16-17 |
| Sun Mar 6, 12:00 ET | vs Virginia South Bend, Ind. | W 12-10 |
| Thu Mar 10, 3:00 ET | at Virginia Tech Blacksburg, Va. | L 12-13 |
| Sun Mar 13, 12:00 ET | vs Jacksonville South Bend, Ind. | W 20-5 |
| Sun Mar 20, 12:00 ET | vs Yale South Bend, Ind. | W 17-10 |
| Sat Mar 26, 1:00 ET | vs Duke South Bend, Ind. | L 12-15 |
| Sat Apr 2, 11:00 AM ET | at North Carolina Chapel Hill, NC | L 7-15 |
| Tue Apr 5 | vs Detroit Mercy South Bend, Ind. | W 27-2 |
| Sat Apr 9, 2:00 ET | at Boston College Chestnut Hill, MA | L 10-16 |
| Sat Apr 16, 12:00 ET | vs Pitt South Bend, Ind. | W 19-7 |
| Mon Apr 18, 2:00 ET | at Marquette Milwaukee, WI | W 19-10 |
| Sat Apr 23, 12:00 ET | at Louisville Louisville, KY | W 15-14 |
| Fri Apr 29, 2:30 ET | vs Duke ACC Championship / Notre Dame, Ind. | W 19-11 |
| Sun May 1, 1:00 ET | vs North Carolina ACC Championship / Notre Dame, Ind. | L 13-14 |
| Fri May 13, 8:00 ET | vs Michigan NCAA Championship / Evanston, Ill. | L 11-17 |