| Date | Game | |
| Fri Feb 10, 7:00 ET | vs San Diego State South Bend, Ind. | W 18-2 |
| Thu Feb 16, 7:00 ET | at Northwestern University Evanston, IL | L 14-18 |
| Sun Feb 19, 3:00 ET | vs Central Michigan South Bend, Ind. | W 24-5 |
| Sat Feb 25, 1:00 ET | vs Clemson South Bend, IN | W 12-9 |
| Sat Mar 4, 1:30 ET | vs Duke Charlotte, N.C. | W 14-6 |
| Sat Mar 11, 12:00 ET | at Syracuse Syracuse, NY | L 7-15 |
| Thu Mar 16, 2:00 ET | vs Virginia Tech South Bend, Ind. | W 14-1 |
| Sun Mar 19, 1:00 ET | vs Liberty South Bend, Ind. | W 19-8 |
| Sat Mar 25, 12:00 ET | at Virginia Charlottesville, VA | L 13-16 |
| Mon Mar 27, 4:00 ET | vs Brown South Bend, Ind. | W 21-7 |
| Sat Apr 1, 12:00 ET | vs North Carolina South Bend, Ind. | W 16-12 |
| Sat Apr 8, 12:00 ET | vs Boston College South Bend, Ind. | L 11-12 |
| Mon Apr 10, 2:00 ET | at Butler Indianapolis, IN | W 26-3 |
| Fri Apr 14, 5:00 ET | at Pitt Pittsburgh, PA | W 17-6 |
| Sun Apr 16, 1:00 ET | at Robert Morris Moon Township, PA | W 21-6 |
| Thu Apr 20, 7:00 ET | vs Louisville South Bend, Ind. | W 15-9 |
| Wed Apr 26, 1:30 ET | vs Virginia Charlotte, NC | W 15-13 |
| Fri Apr 28, 1:00 ET | vs Boston College Charlotte, NC | L 4-9 |
| Fri May 12, 7:00 ET | vs Mercer Gainesville, FL | W 21-6 |
| Sun May 14, 12:00 ET | at Florida Gainesville, FL | W 16-15 |
| Thu May 18, 2:30 ET | at Boston College Chestnut Hill, MA | L 6-20 |