| Date | Game | |
| Fri Feb 6, 7:00 ET | vs Michigan South Bend, Ind. | W 12-10 |
| Sun Feb 8, 1:00 ET | vs Central Michigan South Bend, Ind. | W 25-0 |
| Fri Feb 13, 4:00 ET | at Boston College Chestnut Hill, Mass. | W 12-9 |
| Sun Feb 15, 12:00 ET | at Harvard Cambridge, MA | W 10-7 |
| Sun Feb 22, 4:00 ET | vs Virginia South Bend, Ind. | L 7-9 |
| Sat Feb 28, 12:00 ET | vs Pitt South Bend, Ind. | W 12-9 |
| Sun Mar 8, 12:00 ET | at Clemson Clemson, SC | L 9-13 |
| Tue Mar 10, 2:00 ET | at Elon Elon, NC | W 16-5 |
| Sat Mar 14, 9:00 ET | at Stanford Stanford, CA | ACCNX |
| Sat Mar 21, 1:00 ET | vs Florida State South Bend, Ind. | ACCNX |
| Tue Mar 24, 7:00 ET | vs Robert Morris South Bend, Ind. | ACCNX |
| Sat Mar 28, 1:00 ET | vs California Notre Dame, IN | ACCNX |
| Sat Apr 4, 1:00 ET | at Virginia Tech Blacksburg, VA | ACCNX |
| Mon Apr 6, 1:00 ET | at Liberty Lynchburg, VA | ESPN+ |
| Sat Apr 11, 12:00 ET | at Syracuse Syracuse, NY | ACCNX |
| Thu Apr 16, 5:00 ET | vs Louisville South Bend, Ind. | ACCNX |