| Date | Game | |
| Wed Aug 12, 7:00 ET | vs Samford South Bend, Ind. | T 0-0 |
| Sun Aug 16, 12:00 ET | vs Penn State South Bend, Ind. | T 2-2 |
| Thu Aug 20, 8:00 ET | at Nebraska Lincoln, NE | T 1-1 |
| Sun Aug 23, 1:00 ET | vs Murray State | ACCNX |
| Thu Aug 27, 5:00 ET | at Michigan | BTN+ |
| Thu Sep 3, 7:00 ET | vs Michigan State | ACCNX |
| Sun Sep 6, 12:00 ET | vs IU Indy South Bend, Ind. | |
| Fri Sep 11, 8:00 ET | vs Clemson South Bend, Ind. | |
| Fri Sep 18, 7:00 ET | vs Boston College South Bend, Ind. | |
| Thu Sep 24, 7:00 ET | at Duke Durham, N.C. | |
| Fri Oct 2, 6:00 ET | at North Carolina Chapel Hill, NC | |
| Thu Oct 8, 7:00 ET | vs Virginia South Bend, Ind. | |
| Thu Oct 15, 7:00 ET | vs Pitt South Bend, Ind. | |
| Sat Oct 24, 7:00 ET | at Florida State Tallahassee, FL | |
| Thu Oct 29, 6:00 ET | at California Berkeley, CA | |
| Sun Nov 1, 4:00 ET | at Stanford Stanford, CA | |
| Thu Nov 5, 7:00 ET | vs Miami South Bend, Ind. | |