| Date | Game | |
| Wed Nov 25, 7:00 ET | vs Saint Francis Peterson Events Center, Pittsburgh, PA | L 70-80 |
| Sat Nov 28, 1:00 ET | vs Drexel Peterson Events Center, Pittsburgh, PA | W 83-74 |
| Sat Dec 5, 7:00 ET | vs Northern Illinois Peterson Events Center, Pittsburgh, PA | W 89-59 |
| Wed Dec 9, 9:15 ET | at Northwestern Welsh-Ryan Arena, Evanston, IL | W 71-70 |
| Sat Dec 12, 4:00 ET | vs Gardner-Webb Peterson Events Center, Pittsburgh, PA | W 67-50 |
| Wed Dec 16, 6:00 ET | at Miami Watsco Center, Coral Gables, FL | W 70-55 |
| Tue Dec 22, 7:00 ET | vs Louisville Petersen Events Center, Pittsburgh, PA | L 54-64 |
| Tue Dec 22, 7:00 ET | at Louisville KFC Yum Center, Louisville, KY | |
| Sat Jan 2, 2:00 ET | vs Notre Dame Petersen Events Center, Pittsburgh, PA | ACCN |
| Wed Jan 6, 4:30 ET | at Syracuse The Dome, Syracuse, NY | W 63-60 |
| Sat Jan 16, 12:00 ET | vs Syracuse Petersen Events Center, Pittsburgh, PA | W 96-76 |
| Tue Jan 19, 9:00 ET | vs Duke Petersen Events Center, Pittsburgh, PA | W 79-73 |
| Sat Jan 23, 6:00 ET | at Wake Forest LJVM Coliseum, Winston-Salem, NC | L 75-76 |
| Tue Jan 26, 7:00 ET | vs North Carolina Petersen Events Center, Pittsburgh, PA | L 65-75 |
| Sat Jan 30, 8:00 ET | vs Notre Dame Petersen Events Center, Pittsburgh, PA | L 58-84 |
| Wed Feb 3, 7:00 ET | vs Virginia Tech Petersen Events Center, Pittsburgh, PA | W 83-72 |
| Sat Feb 6, 4:00 ET | at Virginia John Paul Jones Arena, Charlottesville, VA | L 66-73 |
| Sun Feb 7, 12:00 ET | vs Wake Forest Petersen Events Center, Pittsburgh, PA | ACCN |
| Sun Feb 14, 4:00 ET | at Georgia Tech McCamish Pavilion, Atlanta, GA | L 65-71 |
| Wed Feb 17, 4:30 ET | vs NC State Petersen Events Center, Pittsburgh, PA | L 73-74 |
| Sat Feb 20, 4:00 ET | vs Florida State Petersen Events Center, Pittsburgh, PA | L 72-79 |
| Sun Feb 28, 4:00 ET | at NC State PNC Arena, Raleigh, NC | L 62-65 |
| Tue Mar 2, 6:00 ET | vs Wake Forest Petersen Events Center, Pittsburgh, PA | W 70-57 |
| Sat Mar 6, 12:00 ET | at Clemson Littlejohn Coliseum, Clemson, SC | L 62-77 |
| Tue Mar 9, 2:00 ET | vs Miami Greensboro, NC | L 73-79 |