| Date | Game | |
| Thu Aug 21, 8:00 ET | vs Quinnipiac Pittsburgh, PA | W 1-0 |
| Mon Aug 25, 7:00 ET | vs Michigan State Pittsburgh, PA | W 3-2 |
| Fri Aug 29, 7:30 ET | at Georgetown | ESPN+ |
| Fri Sep 5, 6:00 ET | at Clemson | ACCNX |
| Mon Sep 8, 7:00 ET | vs Butler | ACCNX |
| Fri Sep 12, 7:00 ET | vs Notre Dame Pittsburgh, PA | ACCNX |
| Mon Sep 15, 7:00 ET | vs Incarnate Word Pittsburgh, PA | ACCNX |
| Fri Sep 19, 7:00 ET | at Maryland College Park, MD | |
| Fri Sep 26, 7:30 ET | vs NC State Pittsburgh, PA | ACCN |
| Fri Oct 3, 7:00 ET | at Duke Durham, NC | |
| Sat Oct 11, 9:00 ET | at Stanford Stanford, CA | |
| Tue Oct 14, 7:00 ET | vs Denver Pittsburgh, PA | ACCN |
| Sat Oct 18, 7:00 ET | vs Syracuse Pittsburgh, PA | ACCNX |
| Fri Oct 24, 7:30 ET | vs Wake Forest Pittsburgh, PA | ACCN |
| Fri Oct 31, 6:00 ET | at Louisville Louisville, KY | |