| Date | Game | |
| Tue Nov 4, 6:00 ET | vs Drexel Pittsburgh, Pa. | L 60-68 |
| Sat Nov 8, 1:00 ET | vs Mount St. Mary's Pittsburgh, Pa. | W 66-52 |
| Tue Nov 11, 6:00 ET | vs Cornell Pittsburgh, Pa. | W 56-54 |
| Sun Nov 16, 1:00 ET | vs Scranton Pittsburgh, PA | L 63-69 |
| Tue Nov 18, 6:00 ET | vs Le Moyne Pittsburgh, Pa. | W 87-65 |
| Sat Nov 22, 1:00 ET | vs Robert Morris Pittsburgh, Pa. | W 63-54 |
| Tue Nov 25, 6:00 ET | vs Lafayette Pittsburgh, Pa. | L 59-76 |
| Fri Nov 28, 1:15 ET | vs Ball State Naples, FL | L 41-55 |
| Sat Nov 29, 11:00 AM ET | vs Chicago State Naples, FL | W 67-53 |
| Mon Dec 1, 6:00 ET | vs Central Connecticut State Pittsburgh, Pa. | W 68-43 |
| Thu Dec 4, 7:00 ET | at Mississippi State | SEC Network |
| Sun Dec 14, 2:00 ET | at Clemson Clemson, SC | ACCNX |
| Thu Dec 18, 6:00 ET | vs Saint Francis Pittsburgh, Pa. | ACCNX |
| Sun Dec 21, 1:00 ET | at Duquesne Pittsburgh, Pa. | ESPN+ |
| Mon Dec 29, 6:00 ET | at Notre Dame South Bend, Ind. | ACCN |
| Thu Jan 1, 6:00 ET | vs Wake Forest Pittsburgh, PA | ACCNX |
| Sun Jan 4, 6:00 ET | at Boston College Chestnut Hill, MA | ACCN |
| Sun Jan 11, 2:00 ET | at Louisville Louisville, KY | The CW |
| Thu Jan 15, 6:00 ET | vs Florida State Pittsburgh, Pa. | ACCNX |
| Sun Jan 18, 1:00 ET | vs SMU Pittsburgh, Pa. | ACCNX |
| Thu Jan 22, 7:00 ET | at Virginia Charlottesville, VA | ACCNX |
| Sun Jan 25, 2:00 ET | vs Duke Pittsburgh, Pa. | ACCN |
| Thu Jan 29, 6:00 ET | at Virginia Tech Blacksburg, VA | ACCNX |
| Thu Feb 5, 6:00 ET | vs Stanford Pittsburgh, Pa. | ACCNX |
| Sun Feb 8, 1:00 ET | vs California Pittsburgh, Pa. | ACCNX |
| Thu Feb 12, 6:00 ET | vs Syracuse Pittsburgh, PA | ACCNX |
| Sun Feb 15, 12:00 ET | at SMU Dallas, Texas | ACCN |
| Thu Feb 19, 6:00 ET | vs Georgia Tech Pittsburgh, Pa. | ACCNX |
| Sun Feb 22, 12:00 ET | at North Carolina Chapel Hill, NC | ACCN |
| Thu Feb 26, 7:00 ET | at Miami Coral Gables, FL | |
| Sun Mar 1, 2:00 ET | vs NC State Pittsburgh, Pa. | ACCN |