| Date | Game | |
| Sat Sep 3 | vs Louisville Syracuse, N.Y. | W 31-7 |
| Sat Sep 10, 7:00 ET | at UConn East Hartford, Conn. | W 48-14 |
| Sat Sep 17, 12:00 ET | vs Purdue Syracuse, N.Y. | W 32-29 |
| Fri Sep 23, 7:00 ET | vs Virginia Syracuse, N.Y. | W 22-20 |
| Sat Oct 1, 5:00 ET | vs Wagner Syracuse, N.Y. | W 59-0 |
| Sat Oct 15, 3:30 ET | vs NC State Syracuse, N.Y. | W 24-9 |
| Sat Oct 22, 12:00 ET | at Clemson Clemson, S.C. | L 21-27 |
| Sat Oct 29, 12:00 ET | vs Notre Dame Syracuse, N.Y. | L 24-41 |
| Sat Nov 5, 3:30 ET | at Pitt Pittsburgh, Pa. | L 9-19 |
| Sat Nov 12, 8:00 ET | vs Florida State Syracuse, N.Y. | L 3-38 |
| Sat Nov 19, 8:00 ET | at Wake Forest Winston-Salem, N.C. | L 35-45 |
| Sat Nov 26, 7:30 ET | at Boston College Chestnut Hill, Mass. | W 32-23 |
| Thu Dec 29, 2:00 ET | vs Minnesota The Bronx, N.Y. / Bad Boy Mowers Pinstripe Bowl | L 20-28 |