| Date | Game | |
| Tue Nov 9, 7:00 ET | vs Lafayette The Dome, Syracuse, NY | W 97-63 |
| Sun Nov 14, 5:00 ET | vs Drexel The Dome, Syracuse, NY | W 75-60 |
| Sat Nov 20, 5:00 ET | vs Colgate The Dome, Syracuse, NY | L 85-100 |
| Wed Nov 24, 5:00 ET | vs VCU Imperial Arena, Paradise Island, Bahamas | L 55-67 |
| Thu Nov 25, 7:30 ET | vs Arizona State Imperial Arena, Paradise Island, Bahamas | W 92-84 |
| Fri Nov 26, 4:30 ET | vs Auburn Imperial Arena, Paradise Island, Bahamas | L 68-89 |
| Tue Nov 30, 7:00 ET | vs Indiana The Dome, Syracuse, NY | W 112-110 |
| Sat Dec 4, 4:00 ET | at Florida State Donald L. Tucker Civic Center, Tallahassee, FL | W 63-60 |
| Tue Dec 7, 9:30 ET | vs Villanova Madison Square Garden, New York, NY | L 53-67 |
| Sat Dec 11, 12:00 ET | at Georgetown Capital One Arena, Washington, DC | L 75-79 |
| Mon Dec 27, 6:00 ET | vs Brown The Dome, Syracuse, N.Y, | W 93-62 |
| Wed Dec 29, 7:00 ET | vs Cornell The Dome, Syracuse, NY | W 80-68 |
| Sat Jan 1, 6:00 ET | vs Virginia The Dome, Syracuse, NY | L 69-74 |
| Wed Jan 5, 8:00 ET | at Miami Watsco Center, Coral Gables, FL | L 87-88 |
| Sat Jan 8, 2:00 ET | at Wake Forest LJVM Coliseum, Winston-Salem, NC | L 74-77 |
| Tue Jan 11, 7:00 ET | vs Pittsburgh Carrier Dome, Syracuse, NY | W 77-61 |
| Sat Jan 15, 3:00 ET | vs Florida State Carrier Dome, Syracuse, NY | L 71-76 |
| Tue Jan 18, 9:00 ET | vs Clemson Carrier Dome, Syracuse, NY | W 91-78 |
| Sat Jan 22, 12:00 ET | at Duke Cameron Indoor Stadium, Durham, NC | L 59-79 |
| Tue Jan 25, 8:00 ET | at Pitt Petersen Events Center, Pittsburgh, PA | L 53-64 |
| Sat Jan 29, 8:00 ET | vs Wake Forest Carrier Dome, Syracuse, NY | W 94-72 |
| Wed Feb 2, 9:00 ET | at NC State PNC Arena, Raleigh, NC | W 89-82 |
| Sat Feb 5, 2:00 ET | vs Louisville Carrier Dome, Syracuse, NY | W 92-69 |
| Tue Feb 8, 8:00 ET | at Boston College Conte Forum, Chestnut Hill, MA | W 73-64 |
| Sat Feb 12, 6:00 ET | at Virginia Tech Cassell Coliseum, Blacksburg, VA | L 59-71 |
| Sat Feb 19, 12:00 ET | vs Boston College Carrier Dome, Syracuse, NY | W 76-56 |
| Mon Feb 21, 7:00 ET | vs Georgia Tech Carrier Dome, Syracuse, NY | W 74-73 |
| Wed Feb 23, 7:00 ET | at Notre Dame Purcell Pavilion, Notre Dame, IN | L 69-79 |
| Sat Feb 26, 6:00 ET | vs Duke Carrier Dome, Syracuse, NY | L 72-97 |
| Mon Feb 28, 7:00 ET | at North Carolina Smith Center, Chapel Hill, NC | L 79-88 |
| Sat Mar 5, 1:00 ET | vs Miami Carrier Dome, Syracuse, NY | L 72-75 |
| Wed Mar 9, 12:00 ET | vs Florida State Barclays Center, Brooklyn, NY | W 96-57 |
| Thu Mar 10, 12:00 ET | vs Duke Barclays Center, Brooklyn, NY | L 79-88 |