| Date | Game | |
| Mon Nov 2, 7:00 ET | vs New Haven Syracuse, NY | W 74-58 |
| Thu Nov 5, 7:00 ET | vs Central Connecticut State Syracuse, NY | W 102-49 |
| Mon Nov 9, 6:30 ET | vs Indiana Indianapolis, IN | L 80-83 |
| Sun Nov 15, 7:00 ET | at St. John's New York, NY | peacock |
| Wed Nov 18, 8:00 ET | vs Cornell Syracuse, NY | ACCN |
| Sat Nov 21, 2:00 ET | vs Lafayette Syracuse, NY | ACCNX |
| Wed Nov 25, 6:00 ET | vs Albany Syracuse, NY | ACCNX |
| Tue Dec 1, 9:00 ET | at Oklahoma Norman, OK | ESPNU |
| Tue Dec 8, 7:00 ET | vs Colgate Syracuse, NY | ACCNX |
| Sat Dec 12, 5:00 ET | vs Mercyhurst Syracuse, NY | ACCN |
| Wed Dec 16, 7:00 ET | vs Canisius Syracuse, NY | ACCNX |
| Sat Dec 19, 12:00 ET | vs Providence Boston, MA | FOX |
| Tue Dec 22, 4:00 ET | vs Binghamton Syracuse, NY | ACCN |
| Tue Dec 29, 6:00 ET | at Florida State Tallahassee, FL | ACCN |
| Sat Jan 2, 12:00 ET | vs Georgia Tech Syracuse, NY | |
| Tue Jan 5, 7:00 ET | vs Duke Syracuse, NY | |
| Sat Jan 9, 3:00 ET | at Miami Coral Gables, FL | |
| Tue Jan 12, 7:00 ET | at Pittsburgh Pittsburgh, Pa. | |
| Sat Jan 16, 2:00 ET | vs Louisville Syracuse, N.Y. | |
| Tue Jan 19, 7:00 ET | vs Boston College Syracuse, NY | |
| Sat Jan 23, 12:00 ET | vs North Carolina Syracuse, N.Y. | |
| Wed Jan 27 | at Stanford Stanford, CA | |
| Sat Jan 30 | at California Berkeley, Calif. | |
| Wed Feb 3, 9:00 ET | vs Virginia Syracuse, NY | |
| Wed Feb 10 | at Clemson Clemson, SC | |
| Wed Feb 17 | vs Stanford Syracuse, NY | |
| Sat Feb 20 | at Southern Methodist Dallas, Texas | |
| Tue Feb 23, 8:00 ET | vs Pittsburgh Syracuse, N.Y. | |
| Sat Feb 27, 8:00 ET | at Notre Dame South Bend, Ind. | |
| Wed Mar 3, 9:00 ET | at Virginia Tech Blacksburg, VA | |
| Sat Mar 6, 5:30 ET | vs Wake Forest Syracuse, N.Y. | |