| Date | Game | |
| Mon Nov 3, 7:00 ET | vs Charleston Southern Blacksburg, VA | ACCNX |
| Sat Nov 8, 4:00 ET | vs Providence Uncasville, CT | Peacock |
| Wed Nov 12, 7:00 ET | vs Saint Joseph's Blacksburg, VA | ACCNX |
| Sun Nov 16, 2:00 ET | vs Charlotte Blacksburg, VA | ACCNX |
| Wed Nov 19, 7:00 ET | vs Bryant Blacksburg, VA | ACCNX |
| Wed Nov 26, 5:00 ET | vs Colorado State Paradise Island, Bahamas | ESPN2/U |
| Thu Nov 27 | vs Wichita State/Saint Mary's Paradise Island, Bahamas | |
| Fri Nov 28 | vs TBA Paradise Island, Bahamas | |
| Tue Dec 2, 7:00 ET | at South Carolina Columbia, SC | SEC Network |
| Sat Dec 6, 3:00 ET | vs George Mason Blacksburg, VA | ACCNX |
| Thu Dec 11, 7:00 ET | vs Western Carolina Blacksburg, VA | ACCNX |
| Sun Dec 14, 12:00 ET | vs UMES Blacksburg, VA | ACCNX |
| Sat Dec 20, 2:00 ET | vs Elon Blacksburg, VA | ACCNX |
| Wed Dec 31, 2:00 ET | vs Virginia Blacksburg, VA | ACCN |
| Sat Jan 3, 12:00 ET | at Wake Forest Winston-Salem, N.C. | ACCN |
| Wed Jan 7, 7:00 ET | vs Stanford Blacksburg, VA | ACCN |
| Sat Jan 10 | vs California Blacksburg, VA | |
| Tue Jan 13 | at SMU Dallas, Texas | |
| Sat Jan 17, 12:00 ET | vs Notre Dame Blacksburg, VA | ACCN |
| Wed Jan 21, 9:00 ET | at Syracuse Syracuse, NY | |
| Sat Jan 24, 3:30 ET | at Louisville Louisville, KY | The CW |
| Tue Jan 27, 8:00 ET | vs Georgia Tech Blacksburg, VA | ACCN |
| Sat Jan 31, 12:00 ET | vs Duke Blacksburg, VA | ESPN |
| Sat Feb 7, 1:30 ET | at NC State Raleigh, NC | The CW |
| Wed Feb 11, 7:00 ET | at Clemson Clemson, SC | ACCN |
| Sat Feb 14, 2:00 ET | vs Florida State Blacksburg, VA | ACCN |
| Tue Feb 17, 8:00 ET | at Miami Coral Gables, FL | ACCN |
| Sat Feb 21, 12:00 ET | vs Wake Forest Blacksburg, Va. | ACCN |
| Sat Feb 28 | at North Carolina Chapel Hill | ESPN or ESPN2 |
| Tue Mar 3, 9:00 ET | vs Boston College Blacksburg, VA | |
| Sat Mar 7, 12:30 ET | at Virginia Charlottesville, VA | The CW |