| Date | Game | |
| Tue Nov 4, 6:00 ET | vs Towson Blacksburg, VA | W 100-56 |
| Sun Nov 9, 2:00 ET | vs Loyola Maryland Blacksburg, VA | W 64-48 |
| Thu Nov 13, 6:00 ET | vs Gardner-Webb Blacksburg, VA | W 87-51 |
| Sat Nov 15, 2:00 ET | vs Coastal Carolina Blacksburg, VA | W 82-59 |
| Thu Nov 20, 6:00 ET | vs Niagara Blacksburg, VA | W 83-46 |
| Sun Nov 23, 2:00 ET | at James Madison Harrisonburg, VA | L 56-65 |
| Thu Nov 27, 6:30 ET | vs BYU St. Thomas, U.S. Virgin Islands | L 60-64 |
| Sat Nov 29, 2:30 ET | vs Oregon State St. Thomas, U.S. Virgin Islands | W 78-67 |
| Thu Dec 4, 5:00 ET | vs Florida Blacksburg, VA | W 68-64 |
| Sun Dec 7, 2:00 ET | vs Duke Blacksburg, Va. | L 54-70 |
| Wed Dec 10, 6:00 ET | vs Presbyterian Blacksburg, VA | W 92-36 |
| Sun Dec 14, 4:00 ET | vs ETSU Blacksburg, VA | W 73-55 |
| Thu Dec 18, 6:00 ET | at Florida State Tallahassee, Fla. | W 79-54 |
| Sun Dec 21, 12:00 ET | vs Radford Blacksburg, VA | W 79-47 |
| Thu Jan 1, 6:00 ET | vs Miami Blacksburg, VA | L 67-75 |
| Sun Jan 4, 4:00 ET | at Louisville Louisville, KY | L 60-85 |
| Thu Jan 8, 6:00 ET | at Syracuse Syracuse, NY | W 77-57 |
| Sun Jan 11, 12:00 ET | vs Boston College Blacksburg, Va. | W 78-56 |
| Thu Jan 15, 7:30 ET | at SMU | |
| Thu Jan 22, 6:00 ET | vs Clemson Blacksburg, VA | |
| Sun Jan 25, 2:00 ET | at Wake Forest Winston-Salem, N.C. | |
| Thu Jan 29, 6:00 ET | vs Pitt Blacksburg, VA | |
| Sun Feb 1, 2:00 ET | vs Virginia Blacksburg, VA | |
| Thu Feb 5, 7:00 ET | at Notre Dame South Bend, Ind. | |
| Sun Feb 8, 12:00 ET | vs NC State Blacksburg, VA | |
| Thu Feb 12, 10:00 ET | at Stanford Stanford, CA | |
| Sun Feb 15 | at California Berkeley, CA | |
| Thu Feb 19, 6:00 ET | vs North Carolina Blacksburg, VA | |
| Sun Feb 22, 2:00 ET | vs Georgia Tech Blacksburg, VA | |
| Sun Mar 1, 12:00 ET | at Virginia Charlottesville, VA | |