| Date | Game | |
| Fri Aug 29, 10:00 AM ET | vs NC Central Wilmington, NC | |
| Fri Aug 29, 7:00 ET | at UNC-Wilmington Wilmington, NC | |
| Sat Aug 30, 11:00 AM ET | vs Lindenwood Wilmington, NC | |
| Fri Sep 5, 2:00 ET | vs Hampton Newark, DE | |
| Fri Sep 5, 6:00 ET | at Delaware Newark, DE | |
| Sat Sep 6, 1:00 ET | vs Le Moyne Newark, DE | |
| Thu Sep 11, 6:00 ET | vs Marshall Blacksburg, VA | |
| Fri Sep 12, 11:30 AM ET | vs Maryland-Eastern Shore Blacksburg, VA | |
| Fri Sep 12, 7:30 ET | vs Robert Morris Blacksburg, VA | |
| Thu Sep 18, 6:00 ET | vs East Tennessee State Blacksburg, VA | |
| Sat Sep 27, 1:00 ET | vs California Blacksburg, VA | |
| Sun Sep 28, 1:00 ET | vs Stanford Blacksburg, VA | |
| Fri Oct 3, 6:00 ET | vs Syracuse Blacksburg, VA | |
| Sun Oct 5, 1:00 ET | vs Boston College Blacksburg, VA | |
| Sun Oct 12, 1:00 ET | at Notre Dame South Bend, IN | |
| Wed Oct 15, 7:00 ET | vs Virginia Blacksburg, VA | ACCN |
| Sun Oct 19, 1:00 ET | at Virginia Charlottesville, VA | |
| Fri Oct 24, 7:00 ET | at Miami Coral Gables, FL | |
| Fri Oct 31, 6:00 ET | vs Clemson Blacksburg, VA | |
| Sun Nov 2, 1:00 ET | vs Georgia Tech Blacksburg, VA | |
| Wed Nov 26, 3:00 ET | vs Notre Dame Blacksburg, VA | |
| Fri Nov 28 | at Syracuse Syracuse, NY | |