| Date | Game | |
| Tue Nov 9, 9:00 ET | vs Navy John Paul Jones Arena, Charlottesville, VA | L 58-66 |
| Fri Nov 12, 7:00 ET | vs Radford John Paul Jones Arena, Charlottesville, VA | W 73-52 |
| Tue Nov 16, 8:00 ET | at Houston Fertitta Center, Houston, TX | L 47-67 |
| Fri Nov 19, 7:00 ET | vs Coppin State John Paul Jones Arena, Charlottesville, VA | W 68-52 |
| Mon Nov 22, 7:00 ET | vs Georgia Prudential Center, Newark, NJ | W 65-55 |
| Tue Nov 23, 7:30 ET | vs Providence Prudential Center, Newark, NJ | W 58-40 |
| Fri Nov 26, 7:00 ET | vs Lehigh John Paul Jones Arena, Charlottesville, VA | W 61-43 |
| Mon Nov 29, 7:00 ET | vs Iowa John Paul Jones Arena, Charlottesville, VA | L 74-75 |
| Fri Dec 3, 8:00 ET | vs Pittsburgh John Paul Jones Arena, Charlottesville, VA | W 57-56 |
| Tue Dec 7, 6:30 ET | at James Madison Atlantic Union Bank Center, Harrisonburg, VA | L 49-52 |
| Sat Dec 18, 2:00 ET | vs Fairleigh Dickinson John Paul Jones Arena, Charlottesville, VA | W 82-49 |
| Wed Dec 22, 7:00 ET | vs Clemson John Paul Jones Arena, Charlottesville, VA | L 50-67 |
| Sat Jan 1, 6:00 ET | at Syracuse The Dome, Syracuse, NY | W 74-69 |
| Tue Jan 4, 9:00 ET | at Clemson Littlejohn Coliseum, Clemson, SC | W 75-65 |
| Sat Jan 8, 1:00 ET | at North Carolina Smith Center, Chapel Hill, NC | L 58-74 |
| Wed Jan 12, 9:00 ET | vs Virginia Tech John Paul Jones Arena, Charlottesville, VA | W 54-52 |
| Sat Jan 15, 4:30 ET | vs Wake Forest John Paul Jones Arena, Charlottesville, VA | L 55-63 |
| Wed Jan 19, 9:00 ET | at Pitt Petersen Events Center, Pittsburgh, PA | W 66-61 |
| Sat Jan 22, 4:00 ET | at NC State PNC Arena, Raleigh, NC | L 63-77 |
| Mon Jan 24, 7:00 ET | vs Louisville John Paul Jones Arena, Charlottesville, VA | W 64-52 |
| Sat Jan 29, 6:00 ET | at Notre Dame Purcell Pavilion, Notre Dame, IN | L 65-69 |
| Tue Feb 1, 6:00 ET | vs Boston College John Paul Jones Arena, Charlottesville, VA | W 67-55 |
| Sat Feb 5, 5:00 ET | vs Miami John Paul Jones Arena, Charlottesville, VA | W 71-58 |
| Mon Feb 7, 7:00 ET | at Duke Cameron Indoor Stadium, Durham, NC | W 69-68 |
| Sat Feb 12, 4:00 ET | vs Georgia Tech John Paul Jones Arena, Charlottesville, VA | W 63-53 |
| Mon Feb 14, 7:00 ET | at Virginia Tech Cassell Coliseum, Blacksburg, VA | L 53-62 |
| Sat Feb 19, 5:00 ET | at Miami Watsco Center, Coral Gables, FL | W 74-71 |
| Wed Feb 23, 7:00 ET | vs Duke John Paul Jones Arena, Charlottesville, VA | L 61-65 |
| Sat Feb 26, 4:00 ET | vs Florida State John Paul Jones Arena, Charlottesville, VA | L 63-64 |
| Tue Mar 1, 9:00 ET | at Louisville KFC Yum Center, Louisville, KY | |
| Sat Mar 5, 12:00 ET | at Louisville KFC Yum! Center, Louisville, KY | W 71-61 |
| Wed Mar 9, 9:30 ET | vs Louisville Barclays Center, Brooklyn, NY | W 51-50 |
| Thu Mar 10, 9:30 ET | vs North Carolina Barclays Center, Brooklyn, NY | L 43-63 |
| Wed Mar 16, 7:00 ET | vs Mississippi State John Paul Jones Arena, Charlottesville, VA | W 60-57 |
| Sun Mar 20, 6:00 ET | at North Texas Denton, TX | W 71-69 |
| Tue Mar 22, 7:00 ET | vs St. Bonaventure John Paul Jones Arena, Charlottesville, VA | L 51-52 |