| Date | Game | |
| Fri Feb 17, 4:00 ET | vs Youngstown State Winston-Salem, N.C | W 9-3 |
| Sat Feb 18, 4:00 ET | vs Illinois Winston-Salem, N.C | W 8-1 |
| Sun Feb 19, 8:30 AM ET | vs Youngstown State Winston-Salem, N.C | W 18-3 |
| Sun Feb 19, 12:30 ET | vs Illinois Winston-Salem, N.C | W 10-1 |
| Tue Feb 21, 4:00 ET | at UNC Greensboro Greensboro, N.C. | W 20-2 |
| Fri Feb 24, 2:00 ET | vs Mount St. Mary's Winston-Salem, N.C | W 18-2 |
| Fri Feb 24, 6:00 ET | vs Binghamton Winston-Salem, N.C | W 6-0 |
| Sat Feb 25, 6:00 ET | vs Towson Winston-Salem, N.C | W 18-1 |
| Sun Feb 26, 2:00 ET | vs Mount St. Mary's Winston-Salem, N.C | W 15-1 |
| Tue Feb 28, 5:00 ET | vs UNC Wilmington Winston-Salem, N.C | W 8-6 |
| Fri Mar 3, 1:30 ET | vs Purdue Fort Wayne Winston-Salem, N.C | W 11-0 |
| Sat Mar 4, 5:00 ET | vs Ball State Winston-Salem, N.C | W 7-4 |
| Sun Mar 5, 1:00 ET | vs Cornell Winston-Salem, N.C | W 10-3 |
| Tue Mar 7, 4:00 ET | at Coastal Carolina Conway, S.C. | L 11-13 |
| Fri Mar 10, 4:00 ET | at Duke Durham, N.C. | W 8-6 |
| Sat Mar 11, 1:00 ET | at Duke Durham, N.C. | L 1-8 |
| Sat Mar 11, 4:00 ET | at Duke Durham, N.C. | W 5-3 |
| Wed Mar 15, 4:00 ET | at Liberty Lynchburg, Va. | W 12-5 |
| Sat Mar 18, 12:00 ET | vs Notre Dame Winston-Salem, N.C | W 4-1 |
| Sat Mar 18, 4:00 ET | vs Notre Dame Winston-Salem, N.C | W 12-3 |
| Sun Mar 19, 1:00 ET | vs Notre Dame Winston-Salem, N.C | L 1-3 |
| Tue Mar 21, 6:00 ET | vs Elon Winston-Salem, N.C | W 20-0 |
| Fri Mar 24, 8:00 ET | vs Miami Winston-Salem, N.C | W 11-0 |
| Sat Mar 25, 4:00 ET | vs Miami Winston-Salem, N.C | W 4-1 |
| Sun Mar 26, 12:00 ET | vs Miami Winston-Salem, N.C | W 4-1 |
| Tue Mar 28, 5:00 ET | at High Point High Point, NC | W 12-3 |
| Thu Mar 30, 7:00 ET | at Clemson Clemson, S.C. | W 8-3 |
| Fri Mar 31, 6:00 ET | at Clemson Clemson, S.C. | W 4-3 |
| Sat Apr 1, 2:00 ET | at Clemson Clemson, S.C. | W 4-3 |
| Tue Apr 4, 6:00 ET | at Elon Elon, N.C. | L 3-5 |
| Sun Apr 9, 12:00 ET | vs NC State Winston-Salem, N.C | W 6-4 |
| Sun Apr 9, 4:00 ET | vs NC State Winston-Salem, N.C | W 6-3 |
| Tue Apr 11, 6:00 ET | at Appalachian State Boone, NC | W 10-4 |
| Fri Apr 14, 6:00 ET | at Louisville Louisville, Ky. | W 11-5 |
| Sat Apr 15, 1:00 ET | at Louisville Louisville, Ky. | W 3-0 |
| Sun Apr 16, 1:00 ET | at Louisville Louisville, Ky. | L 2-7 |
| Wed Apr 19, 6:00 ET | vs Liberty Winston-Salem, N.C | W 7-4 |
| Thu Apr 20, 7:00 ET | at Pitt Pittsburgh, Pa. | |
| Fri Apr 21, 6:00 ET | at Pitt Pittsburgh, Pa. | L 0-3 |
| Sat Apr 22, 4:00 ET | at Pitt Pittsburgh, Pa. | W 23-4 |
| Sun Apr 23, 1:00 ET | at Pitt Pittsburgh, Pa. | W 17-1 |
| Tue Apr 25, 6:00 ET | vs Coastal Carolina Winston-Salem, N.C | W 11-1 |
| Sat Apr 29, 4:00 ET | vs Wofford Winston-Salem, N.C | W 18-5 |
| Sun Apr 30, 6:00 ET | vs High Point Winston-Salem, N.C | W 15-0 |
| Fri May 5, 8:00 ET | vs Boston College Winston-Salem, N.C | W 6-0 |
| Sat May 6, 4:00 ET | vs Boston College Winston-Salem, N.C | L 9-11 |
| Sun May 7, 12:00 ET | vs Boston College Winston-Salem, N.C | W 4-2 |
| Tue May 9, 6:00 ET | vs UNC Greensboro Winston-Salem, N.C | W 14-4 |
| Fri May 12, 6:00 ET | at Florida State Tallahassee, Fla. | W 10-0 |
| Sat May 13, 12:00 ET | at Florida State Tallahassee, Fla. | W 7-3 |
| Sun May 14, 1:00 ET | at Florida State Tallahassee, Fla. | L 3-4 |
| Tue May 16, 5:00 ET | at UNC Wilmington Wilmington, N.C. | W 4-0 |
| Thu May 18, 6:00 ET | vs Virginia Tech Winston-Salem, N.C | W 6-3 |
| Fri May 19, 6:00 ET | vs Virginia Tech Winston-Salem, N.C | W 7-5 |
| Sat May 20, 1:00 ET | vs Virginia Tech Winston-Salem, N.C | L 6-14 |
| Thu May 25, 11:00 AM ET | vs Pitt Durham, N.C. | W 10-2 |
| Fri May 26, 7:00 ET | vs Notre Dame Durham, N.C. | W 7-5 |
| Sat May 27, 1:00 ET | vs Miami Chapel Hill, NC | L 2-7 |
| Fri Jun 2, 7:00 ET | vs George Mason Winston-Salem, NC | W 12-0 |
| Sat Jun 3, 6:00 ET | vs Maryland Winston-Salem, N.C. | W 21-6 |
| Sun Jun 4, 6:00 ET | vs George Mason Winston-Salem, NC | |
| Sat Jun 10, 12:00 ET | vs Alabama Winston-Salem, NC / NCAA Super Regional | W 5-4 |
| Sun Jun 11, 12:00 ET | vs Alabama Winston-Salem, NC / NCAA Super Regional | W 22-5 |
| Mon Jun 12 | vs Alabama Winston-Salem, NC / NCAA Super Regional (if necessary) | |
| Sat Jun 17, 2:00 ET | vs Stanford Omaha, NE / Men's College World Series | W 3-2 |
| Mon Jun 19, 7:00 ET | vs LSU Omaha, Neb. | W 3-2 |
| Wed Jun 21, 7:00 ET | vs LSU Omaha, Neb. | L 2-5 |
| Thu Jun 22, 7:00 ET | vs LSU Omaha, Neb. | L 0-2 |