| Date | Game | |
| Wed Nov 1 | vs St. Augustine's Exhibition | W 110-79 |
| Sat Nov 11 | vs Pfeiffer Exhibition | W 140-101 |
| Tue Nov 14 | vs Sacred Heart Pre-Season NIT: Charlotte, NC | W 103-81 |
| Wed Nov 15 | vs Winthrop Pre-Season NIT: Charlotte, NC | W 73-66 |
| Sun Nov 19 | vs Gardner-Webb | W 103-50 |
| Wed Nov 22 | vs Gonzaga Pre-Season NIT: New York, NY | L 74-82 |
| Fri Nov 24 | vs Tennessee Pre-Season NIT: New York, NY | W 101-87 |
| Wed Nov 29 | vs Ohio State ACC/Big10 Challenge | W 98-89 |
| Sat Dec 2 | vs Kentucky | W 75-63 |
| Sat Dec 9 | vs High Point | W 94-69 |
| Sat Dec 16 | vs UNC-Asheville | W 93-62 |
| Fri Dec 22 | at St. Louis | W 69-48 |
| Thu Dec 28 | vs Rutgers | W 87-48 |
| Fri Dec 29 | vs Florida Atlantic | W 105-52 |
| Sun Dec 31 | vs Dayton | W 81-51 |
| Wed Jan 3 | vs Penn | W 102-64 |
| Sun Jan 7 | vs Florida State | W 84-58 |
| Wed Jan 10 | vs Virginia | W 79-69 |
| Sat Jan 13 | at Virginia Tech | L 88-94 |
| Wed Jan 17 | at Clemson | W 77-55 |
| Sat Jan 20 | vs Georgia Tech | W 77-61 |
| Wed Jan 24 | at Wake Forest | W 88-60 |
| Sat Jan 27 | at Arizona Lute Olson's worst home loss as Arizona's head coach | W 92-64 |
| Wed Jan 31 | vs Miami | W 105-64 |
| Sat Feb 3 | at N.C. State | L 79-83 |
| Wed Feb 7 | at Duke | W 79-73 |
| Sat Feb 10 | vs Wake Forest | W 104-67 |
| Tue Feb 13 | vs Virginia Tech | L 80-81 |
| Sat Feb 17 | at Boston College | W 77-72 |
| Wed Feb 21 | vs N.C. State | W 83-64 |
| Sun Feb 25 | at Maryland | L 87-89 |
| Thu Mar 1 | at Georgia Tech | L 77-84 |
| Sun Mar 4 | vs Duke Duke's Gerald Henderson throws an elbow that breaks Tyler Hansbrough's nose and bloodies the Smith Center court. | W 86-72 |
| Fri Mar 9 | vs Florida State ACC Tournament: Tampa, FL | W 73-58 |
| Sat Mar 10 | vs Boston College ACC Tournament: Tampa, FL | W 71-56 |
| Sun Mar 11 | vs N.C. State ACC Tournament: Tampa, FL | W 89-80 |
| Thu Mar 15 | vs Eastern Kentucky NCAA R64 - Winston-Salem, NC | W 86-65 |
| Sat Mar 17 | vs Michigan State NCAA R32 - Winston-Salem, NC | W 81-67 |
| Fri Mar 23 | vs Southern California NCAA R16 - East Rutherford, NJ | W 74-64 |
| Sun Mar 25 | vs Georgetown NCAA R8 - East Rutherford, NJ | L 84-96 |